Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales +6 more
wiley +1 more source
High-titer 2-phenylethanol production in Escherichia coli via decarboxylation-step optimization and a vegetable-oil overlay for biocompatible in situ recovery. [PDF]
Liu C +8 more
europepmc +1 more source
While hydration of linoleic acid under formation of (S,Z)‐13‐hydroxyoctadec‐9‐enoic acid is the natural reaction of linoleic acid hydratase from Lactobacillus acidophilus, in this work, it is shown that this enzyme is also capable to catalyze the reverse reaction, namely dehydration.
Laura M. Bernhard +2 more
wiley +1 more source
Sustainable biocatalysis <i>via</i> lipase immobilization: pyrolyzed lignocellulosic bamboo supports in batch and continuous flow systems. [PDF]
Albonetti G +7 more
europepmc +1 more source
Exploiting Biocatalysis for the Scalable Synthesis of Enantiopure γ‐Hydroxynitrile Building Blocks
Screening a panel of (S)‐and (R)‐selective alcohol dehydrogenases identified several biocatalysts for stereoselectively reducing γ‐ketonitriles into γ‐hydroxynitriles. These processes were optimized, delivering the targets in yields up to 88% with e.e.’s up to 99%. Scalability of the methodology was achieved to produce gram quantities of product, which
Benjamin Baumert +7 more
wiley +1 more source
Biocatalytic reduction of nitro-sulfonamides: enzyme engineering, process integration, and sustainable pathways to <i>p</i>-aminobenzenesulfonamide. [PDF]
Ai R +8 more
europepmc +1 more source
Multipoint covalent immobilization of laccase on a modified carbon paper electrode. Robust biointerface with operational stability under chemical, thermal, mechanical, electrical, and storage stress conditions. The practical implementation of enzyme bioelectrodes is limited by the inherent lability of proteins, which require mild conditions to maintain
W. I. García‐García +3 more
wiley +1 more source
Correction: Transdermal delivery of CRISPR/Cas9-mediated melanoma gene therapy via polyamines-modified thermosensitive hydrogels. [PDF]
Li M +8 more
europepmc +1 more source
Cooperative Amidase Systems Control Product Selectivity During Enzymatic Nylon Depolymerization
ABSTRACT Recent advances in enzymatic polyester depolymerization have highlighted the potential of biocatalysis for sustainable plastic recycling. In contrast, efficient enzymatic strategies for polyamide (PA) degradation remain limited. Here, we investigate how complementary amidases influence product formation during the enzymatic treatment of bulk ...
Sukmanita Dewi +7 more
wiley +1 more source
Hijacking host RNA polymerase for processive in situ mutagenesis. [PDF]
Sheng Y, Ni H, Yang S, Hao W, Zhang C.
europepmc +1 more source

