Results 161 to 170 of about 31,860 (265)

Direct Mechanocatalysis and the Pursuit of Green Drug Synthesis

ChemCatChem, Volume 18, Issue 17, 14 September 2026.
We place the strategy of direct mechanocatalysis, in which the milling media itself serves as the catalyst, in the context of pharmaceutical synthesis, critically assessing the current state of the art, existing limitations, and future directions for development in the field.
Maximilian Wohlgemuth, Lars Borchardt, Johanna Templ   +2 more
wiley   +1 more source

Environmental Identification of Novel Enzymes for Polyurethane and Polyamide Degradation

Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.
Heteroatom‐containing plastics such as polyurethanes and nylons are produced at scale yet remain largely unrecycled. Biocatalysts offer a promising route to depolymerization under mild conditions. Here, we present a screening platform for the discovery of novel polyurethane‐ and nylon‐degrading enzymes from environmental samples and demonstrate ...
Malthe Kjær Bendtsen, Andreas Møllebjerg, Samuel Peña‐Díaz, Rosie Graham, Nicolai Claus Petersen, Bjørk Nolsøe Isaksen, Mathias Carstensen, Martin B. Johansen, Andreas Sommerfeldt, Allan R. Petersen, Iddi Khamisi Chuma, Cecilie Ryberg, Thomas Rea Wittenborn, Virginia Gichuru, Huabing Wang, Carsten Scavenius, Alexander Sandahl, Daniel E. Otzen   +17 more
wiley   +2 more sources

Corrigendum to 'Dual-layer microneedles for immunomodulation and infection-responsive therapy in diabetic foot ulcers' [Mater. Today Bio 35 (2025) 102490]. [PDF]

Mater Today Bio
Chen L, Zhan M, Zhang L, Xiong Z, Zhang C, Zhang X, Yang Z, Ma L, Cheng Y, Chen H.   +9 more
europepmc   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 220-249, September 2026.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

Soluble protein analog selection engine (SPASE): An automated AI‐powered server to improve protein engineering workflows

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The design of proteins with desired biophysical properties, such as high solubility and low aggregation propensity, is crucial for various biotechnological and biomedical applications. While deep learning‐based methods like ProteinMPNN have shown remarkable success in protein sequence design, their direct output may not always exhibit optimal ...
Sacha T. Larda, Alex Paré, Nicolas Doucet   +2 more
wiley   +1 more source

Biocatalytic structural diversification of saponins in Zygophyllum decumbens: HR-LC-ESI-TOF-MS/MS profiling and bioactivity modulation. [PDF]

BMC Complement Med Ther
Gabr NM, Abd-ElKhalik SM, Zaki JT, Abdel-Hafez LJM, El-Haddad AE.   +4 more
europepmc   +1 more source

A Review on Green Synthetic Approaches in the Development of Quinoline Analogues

ChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This review highlights recent advances in environmentally friendly approaches, including metal‐free systems, solvent‐free approaches, microwave, and ultrasonic‐assisted techniques, organo‐ and biocatalysis, ionic liquids, nanoparticle catalysis, electrochemical, and photocatalytic strategies for the synthesis of quinoline scaffolds.
Demis Zelelew, Ajay Bissessur, Parvesh Singh, Hogantharanni Govender   +3 more
wiley   +1 more source

Enhanced Biocatalysis in Nanofluidic Membrane Reactors With Goldilocks Nanopores for Enzymes. [PDF]

Small
Oh W, Park JW.
europepmc   +1 more source

3D-Printed Platforms for Enzyme Immobilisation Screening and Direct Translation into Continuous-Flow Biocatalysis. [PDF]

ChemSusChem
Marchetti S, Palmara G, Tinajero C, Lisintuña LD, de Oliveira PR, Zanatta M, Sans V.   +6 more
europepmc   +1 more source

ω‐Hydroxyacid Dehydrogenases From Clostridium viride: Iron‐Containing Biocatalysts With Biotechnological Potential

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
ω‐Hydroxy and ω‐oxo acids are precursors to lactones, polyesters, and nylon‐6, yet selective interconverting enzymes remain scarce. Clostridium viride supplies two iron alcohol dehydrogenases: Cvir‐Hbd2, restricted to C4, and the genomic singleton Cvir‐Hvd, spanning C5–C12 substrates.
Tarik Begic, Julia Hill, Jan L. Stitzel, Lukas Knauer, Volker Schünemann, Markus Räschle, Berta M. Martins, Antonio J. Pierik   +7 more
wiley   +1 more source