Results 151 to 160 of about 32,636 (240)

Molecular Access Engineering for Microbial Biocatalysis: from Enzyme Tunnels to Microbial Cell Factories. [PDF]

J Microbiol Biotechnol
Kim SM.
europepmc   +1 more source

Photometallobiocatalytic Asymmetric Radical‐Mediated Cross‐Coupling of Organotrifluoroborate Salts and Pyridotriazoles

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
An enantioselective photometallobiocatalytic cross‐coupling of pyridotriazoles and secondary alkyltrifluoroborate salts is developed. Cooperative catalysis using eosin B and an engineered protoglobin combines visible‐light‐mediated radical generation with enzymatic metal carbenoid activation, affording valuable N‐heterocyclic products in excellent ...
Huanan Wang, Binh Khanh Mai, Xingjie Zhang, Chongtao Li, Peng Liu, Yang Yang   +5 more
wiley   +2 more sources

A simple strategy for enhancing NADPH-dependent biocatalysis <i>via</i> phosphate analogue-mediated maintenance of the NADPH pool. [PDF]

RSC Adv
Liu R, Liu J, Zhang R, Kuang X, Ma Z, Zhang Q, Xu X, Cheng X, Yang J.   +8 more
europepmc   +1 more source

Chemoenzymatic Synthesis of (4R,7R)‐Zingiberene Enables Construction of nor‐Sesquiterpene Semiochemical Analogs

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
A five‐enzyme chemoenzymatic synthesis of the insect‐repellent (4R,7R)‐zingiberene from the wild tomato (Solanum habrochaites) has been developed. This approach enabled the elucidation of the sesquiterpene synthase cyclization mechanism of (2Z,6Z)‐farnesyl pyrophosphate and bypasses classic biosynthetic constraints of prenyltransferase chain extension ...
Luke A. Johnson, Jennifer C. R. Benton, Chris Jones, Oktawia Kuzba, David J. Miller, John A. Pickett, Rudolf K. Allemann   +6 more
wiley   +1 more source

Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero, Line Mørkholt Lund, Lasse Hyldgaard Klausen, Obinna Markraphael Ajunwa, Mingdong Dong, Rikke Louise Meyer, Victoria Birkedal, Kai Thormann   +7 more
wiley   +2 more sources

A Gas Chromatography‐Based Workflow Leads to the Detection of Hydrogenase Activity in Native Bacteria

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
A standardized gas chromatography–based workflow enables direct functional screening of hydrogenase activity in crude membrane and lysate fractions from native bacteria. Without purification or heterologous expression, hydrogen oxidation is detected across phylogenetically diverse organisms, highlighting the value of activity‐based screening for ...
Marius Stoeckle, Kersten S. Rabe, Christof M. Niemeyer   +2 more
wiley   +1 more source

Predicting Functional Diversity Within Enzyme Families: A Practical Perspective

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
Integrating machine learning into enzyme discovery requires navigating the trade‐offs between data quantity and quality. This article provides a best‐practice framework for developing robust predictors, focusing on mitigating bias in biochemical datasets, implementing systematic “cold‐drug” validation strategies, and utilizing explainable artificial ...
Nika Sokolova, Kristina Haslinger
wiley   +1 more source

The Expanding Reactivity of Cobamide-Containing Proteins: From Mechanistic Understanding to Non-native Biocatalysis. [PDF]

ACS Catal
Kumar A, Lewis JC.
europepmc   +1 more source

Biocatalysis: an efficient and sustainable tool to solve industrial problems?

, 2017
Biocatalysis: an efficient and sustainable tool to solve industrial ...
riva sergio
core  

Reaction-aware molecular representation learning: Toward generalizable artificial intelligence for enzymatic catalysis. [PDF]

Acta Pharm Sin B
Xia K.
europepmc   +1 more source