Results 141 to 150 of about 32,636 (240)
Biocatalysis for Lignin Conversion and Valorization: Driving Sustainability in the Circular Economy
In recent years, lignin derived from lignocellulosic biomass has emerged as a critical component in modern biorefinery systems. The production yield and reactivity of lignin are critical factors for advancing the research and development of lignin ...
Yung-Chuan Liu +5 more
core +1 more source
The FEBS Journal, EarlyView.Cystathionine‐β‐synthase (CBS) helps remove harmful homocysteine and supports the production of protective sulfur‐containing molecules. Using its natural activator, S‐adenosyl‐l‐methionine, as a template, we designed and tested 15 analogues. Three activated and stabilized the enzyme, including the newly identified S‐2‐amino‐adenosyl‐l‐methionine. These
Dalibor Nakládal +18 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.We report the computational design of de novo proteins that bind Mn(salen)‐based complexes (L1) using Rosetta FastDesign and verified by AlphaFold2. After screening, the catalytic activity for the promising design (dnMSBP) toward enantioselective sulfoxidation of thioanisole was optimized based on its crystal structure. With 10 different substrates, we
Jing‐Xiang Wang +6 more
wiley +2 more sources
ChemSusChem, Volume 19, Issue 21, 12 November 2026.Biophotoelectrochemical system merges photoelectrochemical with bioelectrochemical system to enable solar‐driven redox reactions using microorganisms or enzymes. This approach offers multifunctional abilities such as selective H2 production, CO2 reduction, N2 fixation, pollutant removal, and energy recovery, highlighting new pathways for sustainable ...
Indra J. Budiarso +3 more
wiley +1 more source
Lipidomics, Metabolic Engineering, and Biocatalysis: A New Trio for Oilseed Biotechnology. [PDF]
Iran J BiotechnolTorabimehr H, Sajedi RH, Kahrizi D.
europepmc +1 more source
Beyond monofunctionality: structural perspectives on phenol oxidase side activity in a catalase
Acta Crystallographica Section D, Volume 82, Issue 11, Page 1224-1239, November 2026.Structural and biochemical characterization of the extracellular fungal catalase ClCPO uncovers an unexpected phenol oxidase promiscuity. Crystal structures, substrate docking and electron‐transfer pathway analysis identify ligand‐binding regions and support a working mechanistic model for catalase‐associated phenol oxidase activity.Catalases are ...
Christina Ferousi +5 more
wiley +1 more source
Next-Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca. [PDF]
ChembiochemDiaz-Rodriguez A +4 more
europepmc +1 more source
Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles
European Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu +2 more
wiley +1 more source
Author Correction: SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing. [PDF]
Nat CommunHe F +7 more
europepmc +1 more source
Selective N‐Functionalization of Pyrazoles
European Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek +2 more
wiley +1 more source