Flavin-dependent monooxygenases as versatile biocatalysts in biomanufacturing: mechanisms, engineering, and applications. [PDF]
Biotechnol Biofuels BioprodLi Y +7 more
europepmc +1 more source
Plastics and Bioplastics End of Life: A Biocatalytic Perspective
Microbial Biotechnology, Volume 19, Issue 8, August 2026.Biocatalysis links selected conventional plastics and bioplastics to biological routes for polymer transformation, product recovery and end‐of‐life management. Enzymes and microbes enable depolymerisation, upcycling and recovery of monomers, platform chemicals and new materials.
Laura I. de Eugenio +2 more
wiley +1 more source
Redirecting a Native Ene‐Reductase Toward Desaturation With Reverse Enantioselectivity
Angewandte Chemie, Volume 138, Issue 31, 27 July 2026.A native ene‐reductase, XenA, was repurposed to catalyze the reverse‐enantioselective desaturation of cyclohexanones. The final variant was obtained through extensive protein engineering, combining PROSS‐guided computational design with mutagenesis and screening.
Qing‐Qing Zeng +4 more
wiley +2 more sources
Whole-Cell Biocatalysis for the Production of Structurally Diverse Methoxydihydrochalcones: Broad Activity of the <i>Yarrowia</i> Clade. [PDF]
MoleculesChlipała P +4 more
europepmc +1 more source
Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration
Angewandte Chemie, Volume 138, Issue 31, 27 July 2026.The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti +9 more
wiley +2 more sources
Biomimetic Compartmentalization of Enzymes for Sustainable Coenzyme Recycling in Oxidative Photocatalysis. [PDF]
ChembiochemJung MK +10 more
europepmc +1 more source
Dehydration‐driven organization of metabolites into NaDES‐like assemblies in orthodox seeds
New Phytologist, Volume 251, Issue 3, Page 1172-1187, August 2026.Summary Desiccation tolerance in plants, especially during orthodox seed dehydration, relies on compatible solute accumulation, complex molecular mechanisms, and intermolecular organizations that remain poorly understood. We combined metabolite profiling, mass spectrometry imaging, and electrospray and cold‐spray ionization mass spectrometry to ...
Youcef Haddad +11 more
wiley +1 more source
Scaling Up Is Not the Same but Bigger: Overcoming (Some) Limitations in Enzymatic Decarboxylations in Rotating Bed Reactors in Deep Eutectic Solvents. [PDF]
Org Process Res DevVaupel S +3 more
europepmc +1 more source
Light‐Activated Communication Between Synthetic and Living Cells via Photoresponsive Membranes
ChemBioChem, Volume 27, Issue 14, 29 July 2026.Light‐triggered membrane rupture of SCs enables controlled release of adenosine triphosphate (ATP) and histamine, which activate purinergic and histaminergic signaling in HeLa cells, leading to intracellular Ca2+ mobilization. This biomimetic communication platform provides a simple strategy for engineering remotely controlled chemical signaling ...
Roberto Barbaro +8 more
wiley +1 more source