Results 51 to 60 of about 3,414,938 (258)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Clinical, anthropometric, body composition and biochemical characteristics.

open access: yes, 2014
Values in mean±SD (coefficient of variation);* mean (interquartile range).HOMA-IR: Homeostatic model of assessment-insulin resistance; hsCRP: high sensitivity C-reactive protein.Clinical, anthropometric, body composition and biochemical characteristics.
Anant Mohan (134924)   +10 more
core   +1 more source

Effects of Environmental Factors and Nutrient Availability on the Biochemical Composition of Algae for Biofuels Production: A Review

open access: yesEnergies, 2013
Due to significant lipid and carbohydrate production as well as other useful properties such as high production of useful biomolecular substrates (e.g., lipids) and the ability to grow using non-potable water sources, algae are being explored as a ...
Ganti S. Murthy   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Evaluation of biochemical urinary stone composition and its relationship to tap water hardness in Qom province, central Iran

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2011
Mohammad Kazem Moslemi1, Hossein Saghafi2, Seyed Mohammad Amin Joorabchin31Department of Urology, Kamkar Hospital, 2Department of Nephrology, Kamkar Hospital, School of Medicine, 3School of Medicine, Qom University of Medical Sciences, Qom, IranPurpose ...
Moslemi MK, Saghafi H, Joorabchin SMA
doaj  

ECONOMIC VALUE OF SOME LEGUMINOUS PLANT SPECIES OF THE COLLECTIONS FROM THE BOTANICAL GARDEN (INSTITUTE) OF THE ACADEMY OF SCIENCES OF MOLDOVA [PDF]

open access: yesJournal of Plant Development, 2016
The results of the evaluation of the growth and development rates, the seed productivity, the green mass yield, the biochemical composition and the content of amino acids, phosphorous and calcium, the nutritive and energy value of the forage, as well as ...
Alexandru TELEUTA, Victor TITEI
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

FEATURES OF SPIRULINA PLATENSIS CULTIVATED UNDER AUTOTROPHIC AND MIXOTROPHIC CONDITIONS

open access: yesHarčova Nauka ì Tehnologìâ, 2018
Cultivation of Spirulina platensis in Zarrouk media containing 0–20 g l-1 glucose was studied in a photobioreactor for 30 days using a light intensity of 3 klux.
Zahra Rasouli   +2 more
doaj   +1 more source

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