Results 61 to 70 of about 3,414,938 (258)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Growth, biochemical composition and endocrine profiles of normal diploid and pressure, heat and cold shock induced triploids of Oreochromis niloticus were investigated. Triploid females were not significantly different from diploid females in growth rate
Humayun, N M +17 more
core +1 more source
Nannochloris sp. JB17 has been identified as an interesting microalgal species that can tolerate high salinity and high bicarbonate concentrations. In this study, Nannochloris sp.
Giorgos Markou +2 more
doaj +1 more source
The female reproductive system of Chrysoperla sinica was divided into 5 developmental grades according to its anatomic characteristics, and this was verified by the analytical results of the biochemical compositions including nucleic acid, protein ...
XU Yong-yu, HU Cui, MOU Ji-yuan
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
The objective of the present work was to investigate the influence of four diets on population growth, development, total length, dry weight, and nutritional value of two zooplanktonic species, Moina micrura and Diaphanosoma birgei.
L. H. SIPAÚBA-TAVARES, M. A. BACHION
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Mode of access: Internet.Issued by the Columbia university biochemical ...
Columbia University. Biochemical association.
core
Association of IL-6 gene polymorphism with clinical, body composition, anthropometry and biochemical parameters.
S. V. Nandhan (5508662) +5 more
core +1 more source

