Results 161 to 170 of about 579,757 (320)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Kinetics of β-galactosidase Production by Lactobacillus bulgaricus During pH Controlled Batch Fermentation in Three Commercial Bulk Starter Media

Applied Food Biotechnology, 2015
The potential of bulk starter fermentation strategy for production of a cost-effective and GRAS source of β-galactosidase from a starter culture strain Lactobacillus bulgaricus was investigated.
Saeed Abbasalizadeh, Mohammad Amin Hejazi, Mahdi Pesaran Hajiabbas   +2 more
doaj  

Engineering an AlkS‐PalkB Transcription Factor‐Based Biosensor With Improved Sensitivity to Isobutanol and Other Short‐Chain Alcohols

Microbial Biotechnology
Isobutanol, a promising biofuel with higher energy content than ethanol, presents a sustainable alternative through biosynthesis. However, enhancing yield remains challenging due to the inefficiencies in microbial synthesis.
Jiaming Chen, Xizi Wang, Can Zhu, Stefanie Frank, Jian Hao, Frank Baganz   +5 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Biochemical Engineering Approaches for Increasing Viability and Functionality of Probiotic Bacteria. [PDF]

Int J Mol Sci, 2016
Nguyen HT, Truong DH, Kouhoundé S, Ly S, Razafindralambo H, Delvigne F.   +5 more
europepmc   +1 more source

Comprehensive evaluation of T7 promoter for enhanced yield and quality in mRNA production

Scientific Reports
The manufacturing of mRNA vaccines relies on cell-free based systems that are easily scalable and flexible compared with the traditional vaccine manufacturing processes.
Yustika Sari, Sara Sousa Rosa, Jack Jeffries, Marco P. C. Marques   +3 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Synthesis of Lignin Nanoparticles and Their Application in the Stabilization of Water-in-Water Pickering Emulsions: A New Technology for Valorization of Lignin from Sugarcane Bagasse

International Journal of Chemical Engineering
Water-in-water (w/w) emulsions can mimic biological environments, and their stability is ensured by adding nanoparticles capable of adsorbing at liquid-liquid interfaces.
Marcelo da Silva Pedro, Davi Finamori Lopes Feitosa, José Daladiê Barreto da Costa Filho, Nathalia Saraiva Rios, Everaldo Silvino dos Santos, Domingos Fabiano de Santana Souza, Carlos Eduardo de Araújo Padilha, Jackson Araújo de Oliveira   +7 more
doaj   +1 more source

In silico characterization of microbial electrosynthesis for metabolic engineering of biochemicals [PDF]

, 2011
Aditya Vikram Pandit, Radhakrishnan Mahadevan   +1 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source