Results 261 to 270 of about 557,900 (328)

Implementing partial least squares and machine learning regressive models for prediction of drug release in targeted drug delivery application. [PDF]

Sci Rep
Yadav A, Jayaprakash B, Jasim LH, Kundlas M, Anad MY, Srivastava A, Ramudu MJ, Bharathi B, Sahu PK.   +8 more
europepmc   +1 more source

Materials Chemistry and Engineering Laboratory (Chemical Engineering, Materials Engineering), Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka University

Chang Yi Kong
openalex   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Future Frontiers in Bioinspired Implanted Biomaterials. [PDF]

Adv Mater
Gu Q, Yuan R, Sun D, Wallace G.
europepmc   +1 more source

Integrating Biochemical and Computational Approaches Reveal Structural Insights in Trastuzumab scFv-Fc Antibody Engineering

Olga Bednova, Jessica Pougoue Ketchemen, Hazem Mslati, Márk Barok, Heikki Joensuu, Natalie Zeytuni, Francesco Gentile, Léon Sanche, Humphrey Fonge, Jeffrey V. Leyton   +9 more
openalex   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Hinge Truncation to Improve Aggregation Kinetics and Thermal Stability of an Antibody Fab Fragment. [PDF]

Mol Pharm
Zhang C, Karu K, Dalby PA.
europepmc   +1 more source

Rhizosphere Engineering in Saline Soils: Role of PGPR and Organic Manures in Root–Soil Biochemical Interactions for Allium Crops

Tarek Alshaal, Nevien Elhawat, Szilvia Veres   +2 more
openalex   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Engineering Corynebacterium glutamicum cell factory for producing biochemicals

Kai Li, Menglin Sun, Bing Yuan, Cheng Li, Xinqing Zhao, Chen‐Guang Liu, Anthony J. Sinskey, Feng‐Wu Bai   +7 more
openalex   +1 more source