A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Editorial: Effect of mechanical loading on the tendon for tissue engineering approaches. [PDF]
Front Bioeng BiotechnolGögele C +4 more
europepmc +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Retraction notice to "Effect of different etching times on the structural, morphological, electrical, and antimicrobial properties of mesoporous silicon" [Heliyon 9 (2023) e23105]. [PDF]
HeliyonSivaprakash P +6 more
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
AI-Driven Enzyme Engineering: Emerging Models and Next-Generation Biotechnological Applications. [PDF]
MoleculesKhan MF, Khan MT.
europepmc +1 more source
Advanced Biomaterials for Craniofacial Tissue Regeneration: From Fundamental Mechanism to Translational Applications-A Scoping Review. [PDF]
J Funct BiomaterMierzejewska ŻA +5 more
europepmc +1 more source
Correction: Krakowski et al. Cartilage Integrity: A Review of Mechanical and Frictional Properties and Repair Approaches in Osteoarthritis. <i>Healthcare</i> 2024, <i>12</i>, 1648. [PDF]
Healthcare (Basel)Krakowski P +3 more
europepmc +1 more source