Results 271 to 280 of about 3,189,858 (352)

Cell-Free Systems to Mimic and Expand Metabolism. [PDF]

ACS Synth Biol
Rasor BJ, Erb TJ.
europepmc   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

DelaySSA: stochastic simulation of biochemical systems and gene regulatory networks with or without time delays. [PDF]

PLoS Comput Biol
Jin Z, Zhou X, Fang Z.
europepmc   +1 more source

Materials Chemistry and Engineering Laboratory (Chemical Engineering, Materials Engineering), Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka University

Chang Yi Kong
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Key influencers in an aneurysmal thrombosis model: A sensitivity analysis and validation study. [PDF]

APL Bioeng
Liu Q, Lassila T, Lin F, MacRaild M, Patankar T, Islim F, Song S, Xu H, Chen X, Taylor ZA, Sarrami-Foroushani A, Frangi AF.   +11 more
europepmc   +1 more source

Engineering Corynebacterium glutamicum cell factory for producing biochemicals

Kai Li, Menglin Sun, Bing Yuan, Cheng Li, Xinqing Zhao, Chen‐Guang Liu, Anthony J. Sinskey, Feng‐Wu Bai   +7 more
openalex   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Protective effects of 18β-glycyrrhetinic acid on Pasteurella multocida-induced vascular inflammatory injury in mice. [PDF]

Front Vet Sci
Lu Q, Wang L, Jiang X, Han W, Guo P, Liu Y, Fu S, Xiong J, Wu Z, Qiu Y.   +9 more
europepmc   +1 more source