Results 111 to 120 of about 427,584 (269)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Department of Chemistry and Biochemistry Seminar Schedule 2006 Fall
University of Minnesota Duluth. Department of Chemistry and Biochemistry. (2006). Department of Chemistry and Biochemistry Seminar Schedule 2006 Fall.
University of Minnesota Duluth. Department of Chemistry and Biochemistry
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Reforma visokog obrazovanja na sveučilištima u RH temelji se na prihvaćanju Bolonjske deklaracije, koja kao osnovnu zadaću postavlja stvaranje cjelovitog europskog prostora visokog obrazovanja i istraživanja.
Žanić Grubišić, Tihana +1 more
core
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Department of Chemistry and Biochemistry Seminar Schedule 2007 Fall
University of Minnesota Duluth. Department of Chemistry and Biochemistry. (2007). Department of Chemistry and Biochemistry Seminar Schedule 2007 Fall.
University of Minnesota Duluth. Department of Chemistry and Biochemistry
core
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
1st international symposium on the biochemistry of the retina, London, September ...
Graymore, Clive N.,edt +1 more
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
"The present work is a condensation and rewriting of mimeograhed material with considerable additions."--Pref. ; Includes bibliographies. ; Mode of access: Internet.
openaire +1 more source

