Results 151 to 160 of about 1,282,096 (340)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Understanding clinical biochemistry through case-based concept mapping by the students. [PDF]

BMC Med Educ
Chong YP, Thomacos N, Verghese E, Sethi A.   +3 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Correction: Synaptonemal & CO analyzer: a tool for synaptonemal complex and crossover analysis in immunofluorescence images. [PDF]

Front Cell Dev Biol
Soriano J, Belmonte-Tebar A, de la Casa-Esperon E.   +2 more
europepmc   +1 more source

Book Review: Methodical Developments in Biochemistry. Volume 3: Advances with Zonal Rotors [PDF]

, 1974
Derek Raine
openalex   +1 more source

The main research areas of the science school in Ecological Biochemistry of Animals

, 2023
Н. Н. Немова, Н. Н. Немова   +1 more
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Correction: Rapidly decellularized adipose tissue induces soft tissue vascularization in potential anatomical spaces. [PDF]

BMC Biotechnol
Piejko M, Hinz A, Mak P, Ligas E, Misztal K, Janowski M, Wałęga P, Drukała J.   +7 more
europepmc   +1 more source

Teaching Biochemistry using a methodology based on the mental models theory

, 2000
A. M.A. Careiro-Leão, Mia Mayer, Zélia Maria Soares Jófili   +2 more
openalex   +1 more source

BOERHAAVE'S BIOCHEMISTRY [PDF]

Medical History, 1962
openaire   +2 more sources