Results 181 to 190 of about 2,254,748 (322)
Correction: Editorial: Current status and recent advances in preclinical models for rare cancers. [PDF]
Front OncolKrawczyk E, Cavalli LR, Kitlinska J.
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Studies in the biochemistry of micro-organisms [PDF]
, 1940 Winston Kennay Anslow, Harold Raistrick
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
<i>ACS Central Science</i>: Embracing Breadth in Scope and Scientific Topical Representation. [PDF]
ACS Cent SciGarakyaraghi S, Schanze KS.
europepmc +1 more source
The lipid biochemistry of eukaryotic algae.
Progress in lipid research, 2019 Y. Li-Beisson +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Author Correction: Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. [PDF]
Nat Struct Mol BiolCiapponi M +4 more
europepmc +1 more source