Results 191 to 200 of about 1,139,042 (268)

Correction to: Hypoxia-induced histone lactylation promotes pulmonary arterial smooth muscle cells proliferation in pulmonary hypertension. [PDF]

Mol Cell Biochem
Chen A, Chen Z, Huang B, Lian G, Luo L, Xie L.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Association of Serum Uric Acid With Cardiovascular-Kidney-Metabolic Risk in a Rural Indian Population. [PDF]

JACC Asia
Mohanraj S, Vasudevan SA, Raghupathy AK, Seenivasan SN, Durairaj K, Gajendran B, Ayothi P, Baskar MK, Manivel G, Sambandam M, Velmurugan G, Shanmugam J, Cherian M, Alexander T, Swaminathan K, Ramakrishnan A.   +15 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Genetic variants of glucose-dependent insulinotropic polypeptide (GIP) signalling as proxy for body weight reduction and cardiovascular risk. [PDF]

Eur Heart J
Emanuelsson F, Nordestgaard BG, Benn M.
europepmc   +1 more source

Drug-induced plasma discolouration mimicking icterus risks inappropriate withholding of critical lactate. [PDF]

Pract Lab Med
Kerr B, Murphy A, Houstoun C, Tan J, Mykytiv V, Costelloe SJ.   +5 more
europepmc   +1 more source

Dysregulated serum levels of human tissue kallikreins, hK7 and hK10, as potential biomarkers of asthma. [PDF]

Biochem Biophys Rep
Ejaz S, Nasim FU, Abdullah I, Ahmad S, Ashraf M.   +4 more
europepmc   +1 more source

Understanding chemical reactions through multimedia resolution data artistic educational tool (MRDAET). [PDF]

Protein Sci
Pokojná H, Kozlíková B, Furmanová K, Štěpánek A, Kriglstein S.   +4 more
europepmc   +1 more source

Effect of case-based learning biochemistry among first-year medical students. [PDF]

Bioinformation
Singh M, Singh G.
europepmc   +1 more source