Results 211 to 220 of about 2,285,544 (373)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Chemistry, biochemistry, and pharmacology of vitamin B6 and othertopics / [by] W. Korytnyk
, 1973 Wsewolod Korytnyk
openalex +1 more source
Correction: Phytochemical composition, biological activities, and molecular docking studies of ethanolic fruit extract of <i>Tribulus terrestris</i>: an in vitro and in silico approach. [PDF]
3 BiotechSrinivasan MK +3 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Heat exposure modulates redox balance and gonadal-related hormones in Wistar rats. [PDF]
JBRA Assist ReprodRotimi DE, Shalom AE, Adeyemi OS.
europepmc +1 more source