Editorial: Targeting cellular signalling pathways for disease therapy: the potential of cellular reprogramming and protein kinase inhibitors. [PDF]
Marensi V, Oliveira PF, Zamoner A.
europepmc +1 more source
Studies in the Biochemistry of Micro-organisms. Part VIII.—The Estimation of Kojic Acid
John Howard Birkinshaw, Harold Raistrick
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Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
RETRACTED: El-Gowily et al. Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in MCF-7 Breast Cancer Cells. <i>Pharmaceuticals</i> 2021, <i>14</i>, 254. [PDF]
El-Gowily AH+4 more
europepmc +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Rare and common single nucleotide variants in childhood-onset systemic lupus erythematosus. [PDF]
Sayadi A+14 more
europepmc +1 more source
Biochemistry of Depression [PDF]
openaire +2 more sources
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
THE BIOCHEMISTRY OF THE METABOLIC FECAL PROTEIN NITROGEN
Anthony A. Albanese+3 more
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