Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
Correction to: Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via singlecell multiomics analysis. [PDF]
Sheng K+13 more
europepmc +1 more source
THE BIOCHEMISTRY OF THE METABOLIC FECAL PROTEIN NITROGEN
Anthony A. Albanese+3 more
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Corrigendum to: Serum progastrin-releasing peptide in pneumonia, chronic obstructive pulmonary disease and early-stage primary lung cancers. [PDF]
Begolli G+9 more
europepmc +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Corrigendum: Antioxidant, Anti-Alzheimer's, anticancer, and cytotoxic properties of peanut oil: <i>in vitro</i>, <i>in silico</i>, and GC-MS analysis. [PDF]
Djeghim H+6 more
europepmc +1 more source
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
Correction: Metabolomic heterogeneity of ageing with ethnic diversity: a step closer to healthy ageing. [PDF]
Trivedi D+5 more
europepmc +1 more source