Results 31 to 40 of about 477 (119)

Etudes de différentes voies de transduction du signal afin de mettre à jour de nouveaux mécanismes moléculaires et de nouvelles cibles thérapeutiques

, 2020
Lorsque j’ai découvert les sciences physiques et les sciences naturelles, au collège, j’ai été fascinée par ces mondes, « comprendre »…ma vocation était née !
Vallée, Béatrice
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Abstracts

, 2015
Canadian Respiratory Journal, Volume 22, Issue 3, Page e4-e24, 2015.
wiley   +1 more source

Modélisation Moléculaire et simulations: de system biologiques aux matériaux

, 2012
I presently work at the Laboratoire de Biochimie Théorique in the Institut de Biologie et Physico- Chimique (CNRS). I have been hired as researcher (CR1) at CNRS in 2010.
Sterpone, Fabio
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Étude biochimique et biophysique de l’ARN hélicase UPF1 : un moteur moléculaire hautement régulé

, 2018
UPF1 (Up-Frameshift 1) is a multifunctional helicase that unwinds nucleic acids and is conserved throughout the eukaryote kingdom. UPF1 is required for the Nonsense Mediated mRNA Decay (NMD) surveillance pathway, which degrades mRNAs carrying premature ...
Kanaan, Joanne
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Surveillance pathways rescuing eukaryotic ribosomes lost in translation

, 2012
International audienceLiving cells require the continuous production of proteins by the ribosomes. Any problem enforcing these protein factories to stall during mRNA translation may then have deleterious cellular effects.
Bertrand Séraphin, Graille, Marc, Séraphin, Bertrand, Marc Graille   +3 more
core   +1 more source

Abstracts from The Conjoint Annual Meeting of L’Association Des Pneumologues De La Province De QuéBec and Le RéSeau en Santé Respiratoire Du FRSQ

, 2012
Canadian Respiratory Journal, Volume 19, Issue 5, Page e35-e65, 2012.
wiley   +1 more source

Site-directed mutagenesis of wheat 9 kDa lipid transfer protein (LTP)

, 1998
International audienceWheat 9 kDa LTP and four mutants were produced in Escherichia coli and compared with wheat-extracted LTP. Only the Y79 mutant was affected in lipid-binding activity, confirming the position of this residue in the three-dimensionnal ...
Lullien-Pellerin, Valerie, T. Ihorai, Gautier, M-F., M.-F. Gautier, Marion, Didier, M. Ptak, Ihorai, T., Devaux, C., Joudrier, P., C. Devaux, Pitak, M., V. Lullien-Pellerin, P. Joudrier, D. Marion   +13 more
core   +1 more source

Abstracts from the Conjoint Annual Meeting of L’Association des Pneumologues de la Province de Québec and le Réseau en santé Respiratoire du FRSQ

, 2010
Canadian Respiratory Journal, Volume 17, Issue 3, Page e63-e79, 2010.
wiley   +1 more source

Signalisation moléculaire par le système de réparation des mésappariements de l'ADN et l'agent anticancéreux cisplatine : étude des interactions protéine MutS-composé de lésion du cisplatine

, 2007
The DNA mismatch repair (MMR) system participates in the cytotoxicity of the anticancer agent cisplatin by triggering an apoptotic pathway and a deficiency is associated in vivo with cisplatin resistance in cancer cells.
Sedletska, Yuliya
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Dissection of Dom34–Hbs1 reveals independent functions in two RNA quality control pathways

, 2010
International audienceEukaryotic cells have several quality control pathways that rely on translation to detect and degrade defective RNAs. Dom34 and Hbs1 are two proteins that are related to translation termination factors and are involved in no-go ...
Bertrand Séraphin, van den Elzen, Antonia, M G, François Lacroute, Graille, Marc, Marc Graille, Herman van Tilbeurgh, Dominique Durand, Noureddine Lazar, Lazar, Noureddine, van Tilbeurgh, Herman, Julien Henri, Antonia M G van den Elzen, Durand, Dominique, Gas, María, Eugenia, Magali Nicaise, Lacroute, François, Henri, Julien, Séraphin, Bertrand, María Eugenia Gas, Nicaise, Magali   +19 more
core   +1 more source