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Design-for-Trust Techniques for Digital Microfluidic Biochip Layout With Error Control Mechanism⋆*A preliminary version of this paper appeared in the Proc. of IEEE Region 10 Symposium (TENSYMP), 2019 [1].

IEEE/ACM Transactions on Computational Biology & Bioinformatics, 2021
Among recent technological advances, microfluidic biochips have been leading a prominent solution for healthcare and miniaturized bio-laboratories with the assurance of high sensitivity and reconfigurability.
Debasis Gountia, Sudip Roy
semanticscholar   +1 more source

Microfluidic Raman biochip detection of exosomes: a promising tool for prostate cancer diagnosis.

Lab on a Chip, 2020
Tumor-derived exosomes, which contain RNA, DNA, and proteins, are a potentially rich non-invasive source of biomarkers. However, no efficient isolation or detection methods are yet available.
Yanlin Wang   +7 more
semanticscholar   +1 more source

An Ultrasensitive Diagnostic Biochip Based on Biomimetic Periodic Nanostructure-Assisted Rolling Circle Amplification

open access: yesACS Nano, 2018
Developing portable and sensitive devices for point of care detection of low abundance bioactive molecules is highly valuable in early diagnosis of disease.
Jie Wang, Song-Mei Liu, Quan Yuan
exaly   +2 more sources

A nano-integrated microfluidic biochip for enzyme-based point-of-care detection of creatinine.

Chemical Communications, 2021
A nano-integrated portable enzymatic microfluidic electrochemical biochip was developed for single-step point-of-care testing of creatinine. The biochip could automatically eliminate a lot of interferences from practical biological samples and enzymatic ...
Jianyong Li   +8 more
semanticscholar   +1 more source

Simultaneous detection of three biomarkers related to acute myocardial infarction based on immunosensing biochip

Biosensors and Bioelectronics, 2019
An immunosensing biochip for simultaneous detection of three biomarkers related to acute myocardial infarction (AMI) was developed based on anionic soybean peroxidase (SBP) functionalized nanoprobe and chemiluminescent imaging.
Huai-Sheng Wang, Yafeng Wu, Songqin Liu
exaly   +2 more sources

Isolation and analysis of extracellular vesicles in a Morpho butterfly wing-integrated microvortex biochip.

Biosensors & bioelectronics, 2020
With the function of mediating intercellular communication between cells, extracellular vesicles (EVs) have been intently studied for their physiopathology and clinical application values.
Shanying Han   +6 more
semanticscholar   +1 more source

A Sensitive Signal Amplifying Diagnostic Biochip Based on Biomimetic Periodic Nanostructure for Detecting Cancer Exosomes.

ACS Applied Materials and Interfaces, 2020
Tumor derived-exosomes are an emerging noninvasive biomarker reservoirs that reflect biological information from their parental cells, especially specific markers, including proteins, DNA fragments and RNAs.
Junli Zhang   +5 more
semanticscholar   +1 more source

A novel method combining aptamer-Ag10NPs based microfluidic biochip with bright field imaging for detection of KPC-2-expressing bacteria.

Analytica Chimica Acta, 2020
The β-lactam drugs resistance poses a serious threat to human health throughout the world. Klebsiella pneumoniae carbapenemase 2 (KPC-2) is a carbapenemase that produced in bacteria can hydrolyze carbapenems, which typically considered as the antibiotics
J. Chen, Hui Li, Hexin Xie, Danke Xu
semanticscholar   +1 more source

A Machine Learning‐Assisted Nanoparticle‐Printed Biochip for Real‐Time Single Cancer Cell Analysis

Advanced Biosystems, 2020
Cancers are a complex conglomerate of heterogeneous cell populations with varying genotypes and phenotypes. The intercellular heterogeneity within the same tumor and intratumor heterogeneity within various tumors are the leading causes of resistance to ...
Kushal Joshi   +6 more
semanticscholar   +1 more source

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