Results 101 to 110 of about 382,190 (338)

Bilateral Optic Disc Edema in a Patient with Lead Poisoning

open access: yesJournal of Ophthalmic & Vision Research, 2021
Paolo Pigatto, Gianpaolo Guzzi
doaj   +1 more source

A novel combinatory treatment against a CDDP-resistant non-small cell lung cancer based on a Ruthenium(II)-cyclopentadienyl compound

open access: yesPharmacological Research
The therapeutic approach to many solid tumors, including non-small cell lung cancer (NSCLC), is mainly based on the use of platinum-containing anticancer agents and is often characterized by acquired or intrinsic resistance to the drug.
Iris C. Salaroglio   +11 more
doaj   +1 more source

In vivo Assessments of Bioabsorbable AZ91 Magnesium Implants Coated with Nanostructured Fluoridated Hydroxyapatite by MAO/EPD Technique for Biomedical Applications [PDF]

open access: yes, 2015
Although magnesium (Mg) is a unique biodegradable metal which possesses mechanical property similar to that of the natural bone and can be an attractive material to be used as orthopedic implants, its quick corrosion rate restricts its actual clinical ...
Fathi, Mohammadhossein   +4 more
core   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

open access: yesAdvanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu   +5 more
wiley   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

Multi-shell gold nanoparticles functionalized with methotrexate: a novel nanotherapeutic approach for improved antitumoral and antioxidant activity and enhanced biocompatibility

open access: yesDrug Delivery
Methotrexate (MTX) is a folic acid antagonist routinely used in cancer treatment, characterized by poor water solubility and low skin permeability. These issues could be mitigated by using drug delivery systems, such as functionalized gold nanoparticles (
Denisse-Iulia Bostiog   +7 more
doaj   +1 more source

In vitro assessment of cytotoxicity of giomer on human gingival fibroblasts [PDF]

open access: yes, 2009
Root coverage on restored root surfaces has been considered as a challenging issue. The evaluation of cytotoxic effects of restorative materials is a fundamental requirement for sustaining the cell attachment and the clinical success of root coverage ...
Farajnia, S.   +5 more
core   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

open access: yesAdvanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu   +5 more
wiley   +1 more source

Solid-Binding Peptide for Enhancing Biocompatibility of Metallic Biomaterials

open access: yesSynBio
Solid-binding peptides (SBPs) are a powerful tool for surface modification of metallic biomaterials which improve the biocompatibility and functionality of medical devices.
Satoshi Migita
doaj   +1 more source

Effect of Additives on Mineral Trioxide Aggregate Setting Reaction Product Formation [PDF]

open access: yes, 2015
Introduction Mineral trioxide aggregate (MTA) sets via hydration of calcium silicates to yield calcium silicate hydrates and calcium hydroxide (Ca[OH]2). However, a drawback of MTA is its long setting time.
Berzins, David W.   +2 more
core   +1 more source

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