Design and in Vitro Biocompatibility of a Novel Ocular Drug Delivery Device
The capsule drug ring (CDR) is a reservoir and delivery agent, which is designed to be placed within the capsular bag during cataract surgery. Prototypes were manufactured by hot melt extrusion of Bionate II®, a polycarbonate urethane.
Bruce Gale+4 more
doaj +1 more source
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang+6 more
wiley +1 more source
Hydrogels Based Drug Delivery Synthesis, Characterization and Administration
Hydrogels represent 3D polymeric networks specially designed for various medical applications. Due to their porous structure, they are able to swollen and to entrap large amounts of therapeutic agents and other molecules.
Anca Onaciu+4 more
doaj +1 more source
This paper introduces a flexible neural probe with integrated micro‐OLEDs on a flexible substrate for the first time, featuring 8 micro‐OLEDs and recording electrodes for optogenetics. It uses advanced encapsulation and an IAI anode for durability, emitting 470 nm light for ChR2 activation, enabling high‐resolution, minimally invasive stimulation ...
Somin Lee+8 more
wiley +1 more source
Synthesis and Thermal Properties of Novel Biodegradable ABCBA Pentablock Copolymers from Poly (Ethylene glycol), L-Lactide and p-Dioxanone [PDF]
In this work, new biodegradable ABCBA type pentablock copolymers with different mole ratio of L-lactide and PPDO-b-PEG-b-PPDO triblock copolymer were synthesized and characterized.
Jamshid Mohammadi-Rovshandeh+4 more
doaj
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee+6 more
wiley +1 more source
Carbon offers advantages as implant material in human body [PDF]
Because of such characteristics as high strength and long-term biocompatability, aerospace carbonaceous materials may be used as surgical implants to correct pathological conditions in the body resulting from disease or injury.
Benson, J.
core +1 more source
Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies [PDF]
John H. Eldridge+4 more
openalex +1 more source
Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou+2 more
wiley +1 more source
Biointerfacing with AgBiS2 Quantum Dots for Pseudocapacitive Photostimulation
It is demonstrated that AgBiS2 quantum dots exhibit unique photoinduced pseudocapacitive charge transfer properties, enabling efficient light‐to‐electrical energy conversion. These quantum dots facilitate enhanced light absorption and transduction when integrated with ZnO nanowires, which serve as an effective charge transport medium.
Ridvan Balamur+8 more
wiley +1 more source