Results 51 to 60 of about 185,214 (244)

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Development of Chrome-Doped Hydroxyapatite in a PVA Matrix Enriched with Amoxicillin for Biomedical Applications

Antibiotics
Background/Objectives: In this paper, we report the development of the first chrome-doped hydroxyapatite in a poly (vinyl alcohol) (PVA) matrix enriched with amoxicillin for biomedical applications.
Steluta Carmen Ciobanu, Daniela Predoi, Simona Liliana Iconaru, Krzysztof Rokosz, Steinar Raaen, Coralia Bleotu, Mihai Valentin Predoi   +6 more
doaj   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Unveiling the Future: Opportunities in Long-Acting Injectable Drug Development for Veterinary Care

Pharmaceutics
Long-acting injectable (LAI) formulations have revolutionized veterinary pharmaceuticals by improving patient compliance, minimizing dosage frequency, and improving therapeutic efficacy.
HariPriya Koppisetti, Sadikalmahdi Abdella, Deepa D. Nakmode, Fatima Abid, Franklin Afinjuomo, Sangseo Kim, Yunmei Song, Sanjay Garg   +7 more
doaj   +1 more source

Multiscale Structuring of Hydroxyapatite via Two‐Photon Lithography of Nanocomposites

Advanced Functional Materials, EarlyView.
Hydroxyapatite scaffolds are of great interest in bone tissue engineering applications, ranging from 3D cell culture to regenerative medicine. Using two‐photon lithography of a transparent nanocomposite, hydroxyapatite microstructures with features ranging from submicron to centimeter‐scale are fabricated. This allows to mimic the natural bone geometry,
Leonhard Hambitzer, Jan Mathis Hornbostel, Richard Prediger, Sebastian Kluck, Michael Daub, Cornelia Lee‐Thedieck, Frederik Kotz‐Helmer   +6 more
wiley   +1 more source

Colourful Protection: Challenges and Perspectives of Antibacterial Pigments Extracted from Bacteria for Textile Applications

Antibiotics
Bacterial pigments have gained significant attention across multiple industries due to their natural hues and unique functional properties. Beyond coloration, some of these pigments exhibit antibacterial activity, making them particularly valuable in the
Micaela Gomes, Helena P. Felgueiras, Barbara R. Leite, Graça M. B. Soares   +3 more
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Biowaste‐Derived Triboelectric Nanogenerators for Emerging Bioelectronics

Advanced Science
Triboelectric nanogenerators (TENGs) combine contact electrification and electrostatic induction effects to convert waste mechanical energy into electrical energy.
Abhisikta Bhaduri, Tae‐Jun Ha
doaj   +1 more source

Therapeutic Potential of Novel Silver Carbonate Nanostructures in Wound Healing and Antibacterial Activity Against Pseudomonas chengduensis and Staphylococcus aureus

Pharmaceuticals
Background/Objectives: Metallic NPs have been explored for various therapeutic uses owing to utilitarian physicochemical characteristics such as antibacterial, anti-inflammatory, and healing properties.
Tehmina Khan, Ali Umar, Zakia Subhan, Muhammad Saleem Khan, Hafeeza Zafar Ali, Hayat Ullah, Sabeen Sabri, Muhammad Wajid, Rashid Iqbal, Mashooq Ahmad Bhat, Hamid Ali   +10 more
doaj   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source