Results 241 to 250 of about 217,658 (313)

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Bioelectronic synthesis of hydrogen sulfide enables spatiotemporal regulation of protein modification and cellular redox. [PDF]

Sci Adv
Lim L, Lee C, Lee J, Lee M, Kim Y, Lee TK, Lee G, Kim J, Oh SY, Kim J, Park J.   +10 more
europepmc   +1 more source

3D-printing on human acellular dermis for chest wall reconstructions-an <i>in vitro</i> and <i>in ovo</i> study. [PDF]

J Thorac Dis
Grandjean T, Heumüller N, Galata C, Emrich A, Martin M, Wiesmann-Imilowski N, Nickel D, Gercek E, Drees P, Roessner ED, Ritz U.   +10 more
europepmc   +1 more source

Polymeric Materials in Biomedical Engineering: A Bibliometric Mapping. [PDF]

Polymers (Basel)
Veres C, Tănase M, Szabo DA.
europepmc   +1 more source

Eco-sustainable magnetoresistive sensors towards disposable magnetoelectronics. [PDF]

Nat Commun
Guo L, Xu R, Das PT, Oliveros-Mata ES, Peng X, Pylypovskyi OV, Hübner R, Ganss F, Wang X, Li Y, Gepp S, Zabila Y, Bao X, Li S, Zhang Q, Veremchuk I, Janićijević Ž, Baraban L, Voigt C, Mosch S, Gutfleisch O, Li RW, Makarov D.   +22 more
europepmc   +1 more source

The use of a biocompatible carbon fiber implant for cervical and lumbar spine fusion in the treatment of spondylodiscitis: a case report. [PDF]

J Surg Case Rep
Aftab N, Catalan-Lopez RA, Sourani A, Bowers C, Moisi MD.   +4 more
europepmc   +1 more source

Natural Polymers Based Biocompatible Nanomedicines for Targeting Colon Cancer: Prospects and Challenges. [PDF]

Int J Nanomedicine
Wang Q, Liu Z, Jin K.
europepmc   +1 more source