Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin +3 more
wiley +1 more source
Root‐Stimulated Movements in Mimosa Pudica for Biohybrid Robotic Systems
This study demonstrates that thermal and electrical stimulation of Mimosa pudica root induces movement of the petiole and pinnules without direct stimulation of the aerial organs, thereby enabling a plant‐based robotic gripper and providing a foundation for the development of intelligent and sustainable systems.
Misao Sato +6 more
wiley +1 more source
In Vivo Microplastic Detection With Photoacoustic Imaging
ABSTRACT Microplastics are posing an escalating threat to both ecological systems and human health. Yet, current methods for investigating their bioaccumulation are highly invasive, requiring destructive analysis of ex vivo tissues via mass spectrometry, dye labelling, or Raman microspectroscopy.
Joseph C. Bear +9 more
wiley +1 more source
Ecosystem-Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs). [PDF]
Yılmaz Nayır T +4 more
europepmc +1 more source
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Evaluating Environmental Performance of PLA-Cellulose-Based Biocomposites: A Comprehensive Study on Biodegradability, Compostability, and Ecotoxicity. [PDF]
Costa VLD +12 more
europepmc +1 more source
Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou +23 more
wiley +1 more source
Environmental fate, biodegradation pathways, and phytotoxicological risks of biopolymer-based packaging: a critical review. [PDF]
Ferreira DCM +5 more
europepmc +1 more source
Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues
Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak +6 more
wiley +1 more source
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source

