Results 181 to 190 of about 23,264,763 (251)

The effects of bed rest on cardiometabolic health: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract Horizontal bed rest (HBR) and head‐down tilt (HDT) are models of physical inactivity. In this systematic review and meta‐analysis, we aimed to quantify changes in cardiometabolic outcomes during HBR and HDT in healthy adults. Following the PRISMA guidelines, we searched PubMed, Scopus, Web of Science and Cochrane Library until 1 October 2025 ...
Konstantinos Prokopidis, Tyler Daubrah‐Scott, Alyssa Varanoske, Jordi Morwani‐Mangnani, David D. Church, Colleen S. Deane, Bethan E. Phillips, Emily J. Arentson‐Lantz   +7 more
wiley   +1 more source

Metabolic pattern across energy imbalance: An exploratory metabolomics study of female body weight extremes including anorexia nervosa and athletes

Experimental Physiology, EarlyView.
Abstract In anorexia nervosa (AN), prolonged metabolic adaptation to severe energy deficiency can impair treatment efficacy. Similarly, low energy availability poses a recognized risk to athletes, potentially compromising health and performance. This cross‐sectional study aimed to characterize the plasma metabolic pattern of females with varying ...
Sonja Lackner, Olli Kärkkäinen, Sabrina Mörkl, Wolfram Müller, Alfred Fürhapter‐Rieger, Kati Hanhineva, Sandra Johanna Holasek   +6 more
wiley   +1 more source

The effect of repeated hot water immersion on microvascular function, glycaemic control and inflammation in White European and South Asian males

Experimental Physiology, EarlyView.
Abstract Individuals of South Asian (SA) descent display a higher risk for cardiovascular disease and type 2 diabetes mellitus than their White European (WE) counterparts. Heat therapy, such as hot water immersion (HWI), can improve microvascular function and glycaemic control, although effects across racial groups are unknown.
David Bellini, Alex Lloyd, Christof A. Leicht, Stephen J. Bailey, Lewis J. James, Matthew J. Maley   +5 more
wiley   +1 more source

Effects of creatine supplementation on lean mass, muscle size and muscle performance during immobilisation and rehabilitation: A systematic review

Experimental Physiology, EarlyView.
Abstract Creatine monohydrate (CrM) supplementation has established benefits in exercising populations; however, its efficacy during disuse and subsequent rehabilitation remains unclear. This systematic review assessed the effects of CrM supplementation on muscle size, lean mass and muscle performance (strength, power, endurance) during periods of ...
Jedd Pratt, Darren G. Candow, Eric S. Rawson, Scott C. Forbes, Konstantinos Prokopidis   +4 more
wiley   +1 more source

Physical activity partly inhibits autonomic imbalance, immune dysfunction and quality of life induced by chronic shiftwork in policemen

Experimental Physiology, EarlyView.
Abstract Chronic shiftwork can impair autonomic cardiovascular regulation and immune homeostasis. However, the interaction between occupational status and physical activity level in military police officers remains incompletely understood. This cross‐sectional factorial study included 102 men stratified according to occupational status and physical ...
Hélida C. Aquino‐Santos, Jeanne S. Tavares‐Vasconcelos, Anamei Silva‐Reis, Maysa A. R. Brandão‐Rangel, Rayssa T. Morais‐Felix, Fernando A. Santa‐Rosa, André L. L. Bachi, Viviane Soares, Omid Salehian, Claudio R. Frison, Rodolfo P. Vieira, Regiane Albertini   +11 more
wiley   +1 more source

Ventilatory and cerebrovascular responses to exercise in lowlander children acclimatizing to high‐altitude

The Journal of Physiology, EarlyView.
Abstract figure legend To investigate age‐related differences in ventilatory and cerebrovascular responses to exercise at high‐altitude, adults (n = 10, 23–44 years) and children (n = 8, 7–14 years) completed progressive cycling exercise tests at sea‐level and following 6 days of acclimatization at 3800 m.
J. L. Koep, M. G. Rieger, K. J. Smith, G. R. DuManoir, C. M. Tallon, D. R. Perkins, S. Piombo, M. Stembridge, D. M. Cooper, S. Radom‐Aizik, P. N. Ainslie, A. M. McManus   +11 more
wiley   +1 more source

Electrophysiological properties of the dorsal motor nucleus of the vagus motoneurones controlling airway mucus secretion in rats

The Journal of Physiology, EarlyView.
Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza, Renato W. Martins Sá, Luiza Henrique de Souza, Fernando S. Ramalho, Davi J. A. Moraes   +4 more
wiley   +1 more source

Non‐steady‐state modelling reveals reduced skeletal muscle protein synthesis as the primary driver of disuse‐atrophy in young, healthy females

The Journal of Physiology, EarlyView.
Abstract figure legend We used a unilateral model of divergent contractile stimuli, in which one leg was subjected to 10 days of unloading and the contralateral leg was simultaneously subjected to loading. We examined how accounting for changes in protein pool size, using steady‐state and non‐steady‐state modelling approaches, impacted rates of muscle ...
Callum J. Pufahl, Jonathan C. Mcleod, Emily J. Ferguson, Kristine Boileau, Brendan Ross, Thomas R. Tripp, Jennifer A. Wilkinson, Craig A. Simpson, Brendon J. Gurd, Chris McGlory   +9 more
wiley   +1 more source

Sex‐Stratified Associations of DXA‐Derived Adiposity, Regional Fat Distribution and Muscle Power With Incident Hospitalised Cardiovascular Disease in Older Adults: A Prospective Cohort Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11418-11431, December 2026.
ABSTRACT Aims To investigate the sex‐stratified associations of DXA‐derived adiposity, regional fat distribution and muscle power with incident hospitalised cardiovascular disease (CVD) in older Chinese adults. Materials and Methods This prospective cohort included 3168 community‐dwelling older adults (1548 men and 1620 women; median age 72.0 years ...
Ting Zhang, Yuan Gao, Yafei Wu, Jason Leung, Timothy Kwok   +4 more
wiley   +1 more source

Higher Cardiorespiratory Fitness Is Associated With a Lower Burden of Metabolic Syndrome Traits: A Cross‐Sectional Analysis of 39 197 UK Adults

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11608-11620, December 2026.
ABSTRACT Aims To investigate associations of cardiorespiratory fitness (CRF) with metabolic syndrome (MetS) trait count, MetS prevalence and individual MetS traits in a large population‐based cohort. Materials and Methods This cross‐sectional study analysed data for 39 197 adults from a UK‐based independent healthcare charity (mean ± SD: age, 45.8 ± 9 ...
Scott A. Willis, Annalena Phillipp, Kevin Deighton, Christopher Goodwin, Daniel J. Cuthbertson, Shelley E. Keating, Christopher J. A. Pugh, Jonathan G. Stine, Gaël Ennequin, Alexis Couret, David J. Stensel, Guruprasad P. Aithal, Thomas Yates, James A. King   +13 more
wiley   +1 more source