Results 221 to 230 of about 32,726 (302)

Aerobic Exercise Plus Hypocaloric Diet on Serum Leptin Concentrations in Adults With Primary Hypertension and Overweight/Obesity: Results From the EXERDIET‐HTA Trial

open access: yesClinical Obesity, Volume 16, Issue 3, June 2026.
Aerobic exercise plus hypocaloric diet on serum leptin concentrations in adults with primary hypertension and Overweight/Obesity. ABSTRACT Hyperleptinaemia is an emerging mechanism involved in the pathogenesis of obesity‐related primary hypertension (HTN).
Virginia A. Aparicio   +4 more
wiley   +1 more source

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

open access: yesCell Proliferation, Volume 59, Issue 6, June 2026.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang   +8 more
wiley   +1 more source

Intravenous Oxytocin Has no Effect on Ad Libitum Food Intake or Postprandial Plasma Glucose Concentrations in Individuals With Obesity: A Randomised, Placebo‐Controlled, Double‐Blind, Crossover Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4671-4682, June 2026.
ABSTRACT Introduction Oxytocin is expressed throughout the small intestine, suggesting a role for oxytocin in postprandial metabolism. Accordingly, single‐dose intranasal oxytocin reduces food intake and improves glucose tolerance. We investigated the effects of a continuous intravenous oxytocin infusion on ad libitum food intake, appetite sensations ...
Ida M. Gether   +13 more
wiley   +1 more source

SEMASEARCH Study Design: Real‐World Evaluation of Semaglutide 2.4 mg in Adults With Severe Obesity Underrepresented in Clinical Trials

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4602-4609, June 2026.
ABSTRACT Background Although semaglutide 2.4 mg has demonstrated significant weight loss efficacy in clinical trials, real‐world data, particularly with regard to clinically complex and underrepresented populations, remain limited. Objectives The study aims to assess the real‐world effectiveness and patient‐reported outcomes associated with the use of ...
Pierre Bel Lassen   +20 more
wiley   +1 more source

GLP‐1, GIP, and Glucagon Excursions During a Mixed Meal Tolerance Test in Young and Lean South Asians Versus Europids

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5078-5090, June 2026.
ABSTRACT Aims South Asians exhibit an unfavourable metabolic phenotype characterized by visceral obesity, insulin resistance and dyslipidemia. While various hormones play a critical role in regulating postprandial energy metabolism, it remains unclear whether they respond differently to food intake.
Carlijn A. Hoekx   +8 more
wiley   +1 more source

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