Results 101 to 110 of about 449,656 (351)

Development of a simple and versatile in vitro method for production, stimulation, and analysis of bioengineered muscle v1

, 2022
Karen Wells-Cembrano
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Experimental Airway Allogenic Transplantation Model with Decellularized Cryopreserved Tracheas

Biomedicines
Background/Objectives: Tracheal replacement remains an unmet necessity in airway pathology treatment. We describe a decellularization and cryopreservation tracheal replacement protocol tested in vivo.
Néstor J. Martínez-Hernández, Lara Milián-Medina, Jorge Mas-Estellés, Amparo Roig-Bataller, David Hervás-Marín, Manuel Mata-Roig   +5 more
doaj   +1 more source

Bioengineering: Solar upgrade [PDF]

Nature, 2017
Plant scientists are redesigning photosynthesis to improve crop yields and feed a growing population.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Bioengineering 3D Pancreatic Cancer Models with Fibrotic Stroma for In Vitro Cancer Modeling

Micromachines
Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal due to late diagnosis, high malignancy, and profound resistance to therapy. Traditional two-dimensional (2D) cell cultures fail to recapitulate the complex tumor microenvironment (TME ...
Xingrun Lan, Keke Chen, Xiaoyun Wei
doaj   +1 more source

Are short implants in the mandible safe? [PDF]

RGO: Revista Gaúcha de Odontologia, 2009
Objective: To analyze the importance of bioengineering and the improvement in surgical techniques demonstrated by the rates attained of the prevalence of successful placement of dental implants in the posterior region of the mandible, in D3 bone quality ...
Sergio Henrique Gonçalves Motta, Marcelo Barbosa Barros, Flávia Rabello de Mattos, Andrea Leonardo da Silva, Ana Roseli de Queiroz Gonçalves   +4 more
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Considerations and implications of current in vitro model systems to study optic nerve head cellular mechanobiology

Frontiers in Cell and Developmental Biology
The optic nerve head (ONH) is a primary site of biomechanical strain within the eye. Here, tensile, compressive and shear forces can impact both physiologic function and pathologic dysfunction of the tissue.
Ana N. Strat, Ana N. Strat, Preethi S. Ganapathy, Preethi S. Ganapathy, Preethi S. Ganapathy   +4 more
doaj   +1 more source

Pupillometry, a bioengineering overview [PDF]

, 1981
The pupillary control system is examined using a microprocessor based integrative pupillometer. The real time software functions of the microprocessor include: data collection, stimulus generation and area to diameter conversion.
Anchetta, J., Hannaford, B., Myers, G., Peng, P., Sherman, K., Stark, L., Sun, F., Usui, S.   +7 more
core   +1 more source