Results 81 to 90 of about 449,656 (351)

Finite Element Analysis of the Bearing Component of Total Ankle Replacement Implants during the Stance Phase of the Gait Cycle

BioMedInformatics
Total ankle arthroplasty (TAA) is a motion-preserving treatment for end-stage ankle arthritis. An effective tool for analyzing these implants’ mechanical performance and longevity in silico is finite element analysis (FEA).
Timothy S. Jain, Mohammad Noori, Joseph J. Rencis, Amanda Anderson, Naudereh Noori, Scott Hazelwood   +5 more
doaj   +1 more source

Bioengineering horizon scan 2020

eLife, 2020
Horizon scanning is intended to identify the opportunities and threats associated with technological, regulatory and social change. In 2017 some of the present authors conducted a horizon scan for bioengineering (Wintle et al., 2017).
Luke Kemp, Laura Adam, Christian R Boehm, Rainer Breitling, Rocco Casagrande, Malcolm Dando, Appolinaire Djikeng, Nicholas G Evans, Richard Hammond, Kelly Hills, Lauren A Holt, Todd Kuiken, Alemka Markotić, Piers Millett, Johnathan A Napier, Cassidy Nelson, Seán S ÓhÉigeartaigh, Anne Osbourn, Megan J Palmer, Nicola J Patron, Edward Perello, Wibool Piyawattanametha, Vanessa Restrepo-Schild, Clarissa Rios-Rojas, Catherine Rhodes, Anna Roessing, Deborah Scott, Philip Shapira, Christopher Simuntala, Robert DJ Smith, Lalitha S Sundaram, Eriko Takano, Gwyn Uttmark, Bonnie C Wintle, Nadia B Zahra, William J Sutherland   +35 more
doaj   +1 more source

Switchgrass storage effects on the recovery of carbohydrates after liquid hot water pretreatment and enzymatic hydrolysis [PDF]

, 2016
Perennial grasses that would be used for bioenergy and bioproducts production will need to be stored for various periods of time to ensure a continual feedstock supply to a bioprocessing facility. The effects of storage practices on grass composition and
Danielle Julie Carrier, Mark R. Wilkins, Mengxing Li, Michael D. Buser, Noaa Frederick, null null   +5 more
core   +3 more sources

Bioengineered tumor organoids

Current Opinion in Biomedical Engineering, 2020
Recent advances in biofabrication technologies, such as cell culture systems, and biomaterials have led to the development of three-dimensional (3D) cell culture platforms, such as tumor organoids. Tumor organoids are more physiologically accurate to the in vivo system, which they are intended to model, compared with traditional 2D cancer cell culture ...
Anthony Dominijanni, Andrea Mazzocchi, Ethan Shelkey, Steven Forsythe, Mahesh Devarsetty, Shay Soker   +5 more
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

In Vitro Biomechanical Experiment on the Effect of Unilateral Partial Facetectomy Performed by Percutaneous Endoscopy on the Stability of Lumbar Spine

Bioengineering
Objectives: This study’s purpose is to investigate the lumbar biomechanical effects of unilateral partial facetectomy (UPF) of different facet joint (FJ) portions under percutaneous endoscopy.
Tao Ma, Xiaoshuang Tu, Junyang Li, Jingwei Wu, Luming Nong   +4 more
doaj   +1 more source

Assessing the Dynamic Performance of Microbots in Complex Fluid Flows

Applied Sciences, 2016
The use of microbots in biomedicine is a powerful tool that has been an object of study in the last few years. In the special case of using these microdevices in the human circulatory system to remove clots or to deliver drugs, the complex nature of ...
Laura Campo-Deaño
doaj   +1 more source

New Vision for Visual Prostheses

Frontiers in Neuroscience, 2020
Developments of new strategies to restore vision and improving on current strategies by harnessing new advancements in material and electrical sciences, and biological and genetic-based technologies are of upmost health priorities around the world ...
Alexander Farnum, Alexander Farnum, Galit Pelled, Galit Pelled, Galit Pelled   +4 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Improving tumor microenvironment assessment in chip systems through next-generation technology integration

Frontiers in Bioengineering and Biotechnology
The tumor microenvironment (TME) comprises a diverse array of cells, both cancerous and non-cancerous, including stromal cells and immune cells. Complex interactions among these cells play a central role in driving cancer progression, impacting critical ...
Daniela Gaebler, Stephanie J. Hachey, Christopher C. W. Hughes, Christopher C. W. Hughes   +3 more
doaj   +1 more source