Results 61 to 70 of about 334,029 (292)

In Vitro Biomechanical Experiment on the Effect of Unilateral Partial Facetectomy Performed by Percutaneous Endoscopy on the Stability of Lumbar Spine

Bioengineering
Objectives: This study’s purpose is to investigate the lumbar biomechanical effects of unilateral partial facetectomy (UPF) of different facet joint (FJ) portions under percutaneous endoscopy.
Tao Ma, Xiaoshuang Tu, Junyang Li, Jingwei Wu, Luming Nong   +4 more
doaj   +1 more source

Assessing the Dynamic Performance of Microbots in Complex Fluid Flows

Applied Sciences, 2016
The use of microbots in biomedicine is a powerful tool that has been an object of study in the last few years. In the special case of using these microdevices in the human circulatory system to remove clots or to deliver drugs, the complex nature of ...
Laura Campo-Deaño
doaj   +1 more source

New Vision for Visual Prostheses

Frontiers in Neuroscience, 2020
Developments of new strategies to restore vision and improving on current strategies by harnessing new advancements in material and electrical sciences, and biological and genetic-based technologies are of upmost health priorities around the world ...
Alexander Farnum, Alexander Farnum, Galit Pelled, Galit Pelled, Galit Pelled   +4 more
doaj   +1 more source

Esophagus Bioengineering

European Journal of Pediatric Surgery
Abstract Tissue engineering represents a promising and innovative strategy for the treatment of complex congenital and acquired esophageal disorders, particularly in patients for whom conventional therapies have failed or current options for organ replacement remain inadequate. Current approaches have explored the use of synthetic and
Marta, Gazzaneo, Soichi, Shibuya, Natalie, Durkin, Simon, Eaton, Marco, Pellegrini, Paolo, De Coppi   +5 more
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Improving tumor microenvironment assessment in chip systems through next-generation technology integration

Frontiers in Bioengineering and Biotechnology
The tumor microenvironment (TME) comprises a diverse array of cells, both cancerous and non-cancerous, including stromal cells and immune cells. Complex interactions among these cells play a central role in driving cancer progression, impacting critical ...
Daniela Gaebler, Stephanie J. Hachey, Christopher C. W. Hughes, Christopher C. W. Hughes   +3 more
doaj   +1 more source

Perceived Intensity and Discrimination Ability for Lingual Electrotactile Stimulation Depends on Location and Orientation of Electrodes

Frontiers in Human Neuroscience, 2017
Malfunctioning sensory systems can severely impact quality of life and repair is not always possible. One solution, called sensory substitution, is to use another sensory system to bring lost information to the brain. This approach often involves the use
Leslie M. Stone-Roy, Joel Moritz Jr., Philip Turk, John D. Williams   +3 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Current State of the Art in Ventricle Tissue Engineering

Frontiers in Cardiovascular Medicine, 2020
The field of ventricle tissue engineering is focused on bioengineering highly functioning left ventricles that can be used as model systems for basic cardiology research and for cardiotoxicity testing.
Ravi K. Birla
doaj   +1 more source

Bioengineering of the heart [PDF]

APL Bioengineering, 2020
Alberto Redaelli, Justin Cooper-White
openaire   +6 more sources