Results 131 to 140 of about 238,980 (322)
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Офтальмохирургия, 2015 Purpose. To study prerequisites for a development of artificial cornea bioengineered design based on recombinant spidroin tissue matrix by behavior evaluation of 2D (planar) and 3D cell (threedimensional) cultures on its surface.Material and methods.
B. E. Malyugin +12 more
doaj
FEBS Open Bio, EarlyView.We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques +5 more
wiley +1 more source
General method to stabilize mesophilic proteins in hyperthermal water
iScience, 2021 Summary: The stability of protein structures and biological functions at normal temperature is closely linked with the universal aqueous environment of organisms.
Xiaoqian Xin +3 more
doaj
The Enhancement of Drained Salmonid Rivers in lreland - A Bioengineering Perspective [PDF]
, 1993 M. F. O'Grady, John Curtin
openalex +1 more source
A 3D Finite Element evaluation of the exophthalmia reduction [PDF]
Acta of Bioengineering and Biomechanics 4(1) (2003) 166-167, 2006 This paper presents a first evaluation of the feasibility of Finite Element modelling of the orbital decompression, in the context of exophthalmia. First simulations are carried out with data extracted from a patient TDM exam. Results seem to qualitatively validate the feasibility of the simulations, with a Finite Element analysis that converges and ...
arxiv
FEBS Open Bio, EarlyView.The thermophilic acetogenic model organism Moorella thermoacetica can utilize lactate as substrate. The formation of lactate by reduction of pyruvate is energetically favorable, but the reverse reaction, the oxidation of lactate to pyruvate with NAD+ as electron acceptor is challenging.
Florian P. Rosenbaum, Volker Müller
wiley +1 more source
Bioengineering approaches for the endometrial research and application
Materials Today BioThe endometrium undergoes a series of precise monthly changes under the regulation of dynamic levels of ovarian hormones that are characterized by repeated shedding and subsequent regeneration without scarring.
Wanlin Dai +6 more
doaj
Staged Self-Assembly:Nanomanufacture of Arbitrary Shapes with O(1) Glues [PDF]
arXiv, 2008 We introduce staged self-assembly of Wang tiles, where tiles can be added dynamically in sequence and where intermediate constructions can be stored for later mixing. This model and its various constraints and performance measures are motivated by a practical nanofabrication scenario through protein-based bioengineering.
arxiv
FEBS Open Bio, EarlyView.IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He +5 more
wiley +1 more source