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Bioengineering [PDF]

open access: yes, 2015
In this entry, the field of bioengineering will be discussed, including the large field of biomedical engineering and the nonmedical fields of biosystems and bioprocess engineering and biomimetics. The focus is on ethical issues in bioengineering. Associated ethical issues include clinical-related issues concerning manipulation of the human genome, the
Brey, Philip A.E., Nagel, Saskia K.
openaire   +2 more sources

Book Review: Further understanding of the human machine. The road to bioengineering

open access: yesBioMedical Engineering OnLine, 2017
Book details Max E. Valentinuzzi (editor) Further understanding of the human machine. The road to bioengineering Series on bioengineering and biomedical engineering, volume 7. Singapore/New Jersey: World Scientific Publishing Co. Pte. Ltd. pp.
Alvin Wald
doaj   +1 more source

Automatic Segmentation of Exudates in Ocular Images using Ensembles of Aperture Filters and Logistic Regression [PDF]

open access: yes, 2013
Hard and soft exudates are the main signs of diabetic macular edema (DME). The segmentation of both kinds of exudates generates valuable information not only for the diagnosis of DME, but also for treatment, which helps to avoid vision loss and blindness.
Ballarin, Virginia Laura   +2 more
core   +1 more source

Hybrid bioprinting of chondrogenically induced human mesenchymal stem cell spheroids [PDF]

open access: yes, 2020
To date, the treatment of articular cartilage lesions remains challenging. A promising strategy for the development of new regenerative therapies is hybrid bioprinting, combining the principles of developmental biology, biomaterial science, and 3D ...
Asadian, Mahtab   +8 more
core   +2 more sources

The matrix in focus: new directions in extracellular matrix research from the 2021 ASMB hybrid meeting

open access: yesBiology Open, 2022
The extracellular matrix (ECM) is a complex assembly of macromolecules that provides both architectural support and molecular signals to cells and modulate their behaviors.
Bryan A. Nerger   +10 more
doaj   +1 more source

Synergistic Model of Cardiac Function with a Heart Assist Device [PDF]

open access: yes, 2019
The breakdown of cardiac self-organization leads to heart diseases and failure, the number one cause of death worldwide. The left ventricular pressure–volume relation plays a key role in the diagnosis and treatment of heart diseases.
Bestel, Haken, Knudsen, Simaan, Tuzun
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

General method to stabilize mesophilic proteins in hyperthermal water

open access: yesiScience, 2021
Summary: The stability of protein structures and biological functions at normal temperature is closely linked with the universal aqueous environment of organisms.
Xiaoqian Xin   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Bioengineering liver microtissues for modeling non-alcoholic fatty liver disease

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
Non-alcoholic fatty liver disease (NAFLD) has become the world’s most common chronic liver disease. However, due to the lack of reliable in vitro NAFLD models, drug development studies have faced many limitations, and there is no food and drug ...
Negar Aasadollahei   +5 more
doaj   +1 more source

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