Results 51 to 60 of about 25,979 (196)
Bioethical Issues in the Management of Gender Dysphoria [PDF]
, 2011 The term gender dysphoria ( I) describes a heterogeneous group of individuals who express varying degrees of dissatisfaction with their anatomic gender (hence gender dysphoria ), and the desire to possess the secondary sexual characteristics of the ...
Brown, MD, George R.
core +1 more source
Disentangling informing participants from obtaining their consent
Learning Health Systems, EarlyView.Abstract Introduction Pragmatic clinical trials conducted in the context of routine care frequently satisfy the regulatory criteria for a waiver of research consent. When they do, investigators and Institutional Review Boards might assume that there is no reason to communicate any information regarding the study to participants.
Patricia Pearl O'Rourke +15 more
wiley +1 more source
The Network of Services for COVID-19 Vaccination in Persons With Mental Disorders: The Italian Social Health System, Its Organization, and Bioethical Issues. [PDF]
Front Public Health, 2022 Scendoni R, Fedeli P, Cingolani M.
europepmc +1 more source
A framework for health systems to assess and prioritize participation in pragmatic clinical trials
Learning Health Systems, EarlyView.Abstract Introduction Pragmatic clinical trials (PCTs) are frequently embedded within settings in which patients receive their routine clinical care. The health care institutions that deliver routine clinical care must therefore decide how they prioritize PCTs in comparison to other institutional priorities. Yet no formal guidance yet exists to support
Stephanie R. Morain +2 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Dopaminergic neuron depletion in the substantia nigra (SN) and the pathological aggregation of α‐synuclein are the neuropathological hallmarks of Parkinson's disease (PD). Objectives This study aimed to investigate the association between the polygenic risk score for PD (PD‐PRS) and transcranial sonography (TCS)‐measured SN ...
Mart Kals +11 more
wiley +1 more source
Ethical aspects in managing patients diagnosed with digestive cancers; a review of literature [PDF]
, 2019 Numerous bioethical recommendations are now available in the complex process of communication with cancer patients. In this review, we have focused on the complex process of managing patients with different types of oncologic digestive diseases ...
Andreea, Gheorghe +9 more
core +1 more source
CRISPR-Cas and Its Wide-Ranging Applications: From Human Genome Editing to Environmental Implications, Technical Limitations, Hazards and Bioethical Issues. [PDF]
Cells, 2021 Piergentili R +5 more
europepmc +1 more source
The Socio-genetic marginalization in Asia programme (SMAP) [PDF]
, 2005 SMAP, the Socio-genetic Marginalization in Asia Programme, which started off in August 2004, is a research programme set up with the support of the Netherlands Science Organisation (NWO), IIAS, and the Amsterdam School for Social Science Research (ASSR).
Sleeboom-Faulkner, Margaret
core
Molecular Nutrition &Food Research, EarlyView.The postprandial glycemia of healthy adults is not downregulated by the coadministration of a sugar solution and a wine by‐product enriched beverage due to the high variability in the response. Blood phenolic compounds of responders’ volunteers are not associated with the reduction effect of postprandial hyperglycemia.
María‐José Motilva +2 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Platform trials present several advantages over traditional interventional clinical trials. Here, we provide a detailed description of the operational framework of the HEALEY ALS Platform Trial. Methods Platform‐level procedures for regulatory oversight, safety, and site management were developed prior to trial launch ...
Brittney A. Harkey +279 more
wiley +1 more source