Results 21 to 30 of about 680 (138)

Old World camels in a modern world – a balancing act between conservation and genetic improvement

Animal Genetics, Volume 50, Issue 6, Page 598-612, December 2019., 2019
Summary Old World camels have served humans in cross‐continental caravans, transporting people and goods, connecting different cultures and providing milk, meat, wool and draught since their domestication around 3000–6000 years ago. In a world of modern transport and fast connectivity, these beasts of burden seem to be out‐dated.
P. A. Burger, E. Ciani, B. Faye
wiley   +1 more source

Los sistemas vegetales como plataformas de producción de proteínas de interés para la industria farmacéutica

Dominguezia, 2020
La biotecnología vegetal logró armonizar los nuevos desarrollos relacionados con los sistemas productivos vegetales con la necesidad de proteínas recombinantes de la industria farmacéutica.
María Alejandra Alvarez
doaj   +2 more sources

Angiotensin‐(1‐7) and Alamandine Promote Anti‐inflammatory Response in Macrophages In Vitro and In Vivo

Mediators of Inflammation, Volume 2019, Issue 1, 2019., 2019
The renin‐angiotensin system (RAS) peptides play an important role in inflammation. Resolution of inflammation contributes to restore tissue homeostasis, and it is characterized by neutrophil apoptosis and their subsequent removal by macrophages, which are remarkable plastic cells involved in the pathophysiology of diverse inflammatory diseases ...
Melissa de Carvalho Santuchi, Miriane Fernandes Dutra, Juliana Priscila Vago, Kátia Maciel Lima, Izabela Galvão, Fernando Pedro de Souza-Neto, Mario Morais e Silva, Aline Cristina Oliveira, Flávia Carvalho Bittencourt de Oliveira, Ricardo Gonçalves, Mauro Martins Teixeira, Lirlândia Pires Sousa, Robson Augusto Souza dos Santos, Rafaela Fernandes da Silva, Michele T. Pritchard   +14 more
wiley   +1 more source

Evaluación Biofarmacéutica y Farmacocinética Poblacional de Levetiracetam en Pacientes Epilépticos [PDF]

, 2020
Levetiracetam es un fármaco antiepiléptico que se emplea para tratar todo tipo de crisis epilépticas en pacientes de todas las edades. El objetivo de este estudio fue evaluar la calidad biofarmacéutica del medicamento innovador y de 4 productos genéricos
MARIA PATRICIA HERNANDEZ MITRE;592618, Hernández Mitre, María Patricia   +1 more
core   +1 more source

Desordens informativas: análise de pronunciamentos de Jair Bolsonaro contra a vacinação de covid-19

RECIIS, 2023
Baseando-se nos conceitos de “desordens informativas” propostos por Claire Wardle e Hossein Derakhshan, este trabalho propõe-se a observar o fenômeno de hesitação vacinal e a opinião pública em relação à vacina CoronaVac contra a covid-19, a partir da ...
Alice Agnes Spíndola Mota, Sidiany Mendes Pimentel, Albertina Vieira de Melo Gomes Oliveira   +2 more
doaj   +1 more source

A New Platelet‐Aggregation‐Inhibiting Factor Isolated from Bothrops moojeni Snake Venom

BioMed Research International, Volume 2017, Issue 1, 2017., 2017
This work reports the purification and functional characterization of BmooPAi, a platelet‐aggregation‐inhibiting factor from Bothrops moojeni snake venom. The toxin was purified by a combination of three chromatographic steps (ion‐exchange on DEAE‐Sephacel, molecular exclusion on Sephadex G‐75, and affinity chromatography on HiTrap™ Heparin HP ...
Bruna Barbosa de Sousa, Carla Cristine Neves Mamede, Mariana Santos Matias, Déborah Fernanda da Cunha Pereira, Mayara Ribeiro de Queiroz, Edigar Henrique Vaz Dias, Anielle Christine Almeida Silva, Noelio Oliveira Dantas, Júnia de Oliveira Costa, Fábio de Oliveira, Ji-Fu Wei   +10 more
wiley   +1 more source

Alteration of ROS Homeostasis and Decreased Lifespan in S. cerevisiae Elicited by Deletion of the Mitochondrial Translocator FLX1

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
This paper deals with the control exerted by the mitochondrial translocator FLX1, which catalyzes the movement of the redox cofactor FAD across the mitochondrial membrane, on the efficiency of ATP production, ROS homeostasis, and lifespan of S. cerevisiae.
Teresa Anna Giancaspero, Emilia Dipalo, Angelica Miccolis, Eckhard Boles, Michele Caselle, Maria Barile, Dina Bellizzi   +6 more
wiley   +1 more source

Rapid Purification of a New P‐I Class Metalloproteinase from Bothrops moojeni Venom with Antiplatelet Activity

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
The present study aimed to evaluate the proteolytic and biological activities of a new metalloproteinase from B. moojeni venom. The purification of BmooMPα‐II was carried out through two chromatographic steps (ion‐exchange and affinity). BmooMPα‐II is a monomeric protein with an apparent molecular mass of 22.5 kDa on SDS‐PAGE 14% under nonreducing ...
Mayara R. de Queiroz, Carla C. Neves Mamede, Kelly C. Fonseca, Nadia C. G. de Morais, Bruna B. de Sousa, Norival A. Santos-Filho, Marcelo E. Beletti, Eliane C. Arantes, Leonilda Stanziola, Fábio de Oliveira, Jozef Anné   +10 more
wiley   +1 more source

INDÚSTRIA BIOFARMACÊUTICA E SEU PROCESSO PRODUTIVO

Evidência, 2015
A biotecnologia aplicada na produção de medicamentos vem se tornando uma área economicamente estratégica dentro das grandes indústrias farmacêuticas.
Ingrid Albrecht, Sandro Augusto Rhoden, João Alencar Pamphile   +2 more
doaj   +1 more source

Purification and Characterization of BmooAi: A New Toxin from Bothrops moojeni Snake Venom That Inhibits Platelet Aggregation

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
In this paper, we describe the purification/characterization of BmooAi, a new toxin from Bothrops moojeni that inhibits platelet aggregation. The purification of BmooAi was carried out through three chromatographic steps (ion‐exchange on a DEAE‐Sephacel column, molecular exclusion on a Sephadex G‐75 column, and reverse‐phase HPLC chromatography on a C2/
Mayara Ribeiro de Queiroz, Carla Cristine N. Mamede, Nadia Cristina G. de Morais, Kelly Cortes Fonseca, Bruna Barbosa de Sousa, Thaís M. Migliorini, Déborah Fernanda C. Pereira, Leonilda Stanziola, Leonardo A. Calderon, Rodrigo Simões-Silva, Andreimar Martins Soares, Fábio de Oliveira, Phillip I. Bird   +12 more
wiley   +1 more source