Results 31 to 40 of about 477 (144)

INDÚSTRIA BIOFARMACÊUTICA E SEU PROCESSO PRODUTIVO

open access: yesEvidência, 2015
A biotecnologia aplicada na produção de medicamentos vem se tornando uma área economicamente estratégica dentro das grandes indústrias farmacêuticas.
Ingrid Albrecht   +2 more
doaj   +1 more source

Purification and Characterization of BmooAi: A New Toxin from Bothrops moojeni Snake Venom That Inhibits Platelet Aggregation

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
In this paper, we describe the purification/characterization of BmooAi, a new toxin from Bothrops moojeni that inhibits platelet aggregation. The purification of BmooAi was carried out through three chromatographic steps (ion‐exchange on a DEAE‐Sephacel column, molecular exclusion on a Sephadex G‐75 column, and reverse‐phase HPLC chromatography on a C2/
Mayara Ribeiro de Queiroz   +12 more
wiley   +1 more source

Estudio comparativo de la calidad biofarmacéutica de Clonazepam 0,5 mg comercializados en el mercado peruano

open access: yesArs Pharmaceutica, 2021
RESUMEN Introducción: el Clonazepam pertenece a un grupo de medicamentos llamados benzodiazepinas. Se sabe que estos medicamentos actúan en el cerebro a través del GABA.
Lennin Rodriguez-Saavedra   +2 more
doaj   +1 more source

Strychnos pseudoquina and Its Purified Compounds Present an Effective In Vitro Antileishmanial Activity

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
The development of new and cost‐effective alternative therapeutic strategies to treat leishmaniasis has become a high priority. In the present study, the antileishmanial activity of Strychnos pseudoquina St. Hil. was investigated and pure compounds that presented this biological effect were isolated. An ethyl acetate extract was prepared, and it proved
Paula Sousa Lage   +15 more
wiley   +1 more source

Requisitos de bioisenção com base no Sistema de Classificação Biofarmacêutica no Brasil e no mundo

open access: yesRevista de Direito Sanitário, 2022
O acesso a medicamentos pode ser facilitado por programas globais de desenvolvimento farmacêutico, mas há necessidade de que as agencias regulatórias e as indústrias farmoquímicas e farmacêuticas interajam e haja um consenso quanto as exigências para o ...
Valéria Sant'Anna Dantas Esteves   +2 more
doaj  

GESTIÓN DE PROPIEDAD INDUSTRIAL DEL CICLO DE VIDA DEL PRODUCTO/PROYECTO EN UNA EMPRESA BIOFARMACÉUTICA CUBANA

open access: yesRevista Cubana de Administración Pública y Empresarial, 2022
El Centro de Investigación y Desarrollo de Medicamentos (CIDEM) es una empresa del Grupo de las Industrias Biotecnológica y Farmacéutica de Cuba (BioCubaFarma) que se dedica a la investigación y desarrollo de medicamentos genéricos, innovadores y de ...
Amarilys Casalis Viamontes   +3 more
doaj   +1 more source

ASPic‐GeneID: A Lightweight Pipeline for Gene Prediction and Alternative Isoforms Detection

open access: yesBioMed Research International, Volume 2013, Issue 1, 2013., 2013
New genomes are being sequenced at an increasingly rapid rate, far outpacing the rate at which manual gene annotation can be performed. Automated genome annotation is thus necessitated by this growth in genome projects; however, full‐fledged annotation systems are usually home‐grown and customized to a particular genome.
Tyler Alioto   +4 more
wiley   +1 more source

A Regulatory Role of NAD Redox Status on Flavin Cofactor Homeostasis in S. cerevisiae Mitochondria

open access: yesOxidative Medicine and Cellular Longevity, Volume 2013, Issue 1, 2013., 2013
Flavin adenine dinucleotide (FAD) and nicotinamide adenine dinucleotide (NAD) are two redox cofactors of pivotal importance for mitochondrial functionality and cellular redox balance. Despite their relevance, the mechanism by which intramitochondrial NAD(H) and FAD levels are maintained remains quite unclear in Saccharomyces cerevisiae. We investigated
Teresa Anna Giancaspero   +3 more
wiley   +1 more source

Bmoo FIBMP‐I: A New Fibrinogenolytic Metalloproteinase from Bothrops moojeni Snake Venom

open access: yesInternational Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
A new fibrinogenolytic metalloproteinase (Bmoo FIBMP‐I) was purified from Bothrops moojeni snake venom. This enzyme was isolated through a combination of three chromatographic steps (ion‐exchange, molecular exclusion, and affinity chromatography). Analyses by reverse phase chromatography, followed by mass spectrometry, showed the presence of enzyme ...
F. S. Torres   +10 more
wiley   +1 more source

Procedimiento para la caracterización socio psicológica de cuadros: caso de estudio en empresa biofarmacéutica

open access: yesRevista Cubana de Administración Pública y Empresarial
La caracterización socio psicológica es un método que contribuye a identificar las características, preparación técnico-profesional, así como las perspectivas de desarrollo de los cuadros, posibilitando su mejor ubicación y desempeño en las ...
Bárbara Susana Sánchez Vignau   +3 more
doaj   +1 more source

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