Results 31 to 40 of about 1,385 (152)

Requisitos de bioisenção com base no Sistema de Classificação Biofarmacêutica no Brasil e no mundo

Revista de Direito Sanitário, 2022
O acesso a medicamentos pode ser facilitado por programas globais de desenvolvimento farmacêutico, mas há necessidade de que as agencias regulatórias e as indústrias farmoquímicas e farmacêuticas interajam e haja um consenso quanto as exigências para o ...
Valéria Sant'Anna Dantas Esteves, Laís Bastos da Fonseca, Kátia Christina Leandro   +2 more
doaj  

ASPic‐GeneID: A Lightweight Pipeline for Gene Prediction and Alternative Isoforms Detection

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
New genomes are being sequenced at an increasingly rapid rate, far outpacing the rate at which manual gene annotation can be performed. Automated genome annotation is thus necessitated by this growth in genome projects; however, full‐fledged annotation systems are usually home‐grown and customized to a particular genome.
Tyler Alioto, Ernesto Picardi, Roderic Guigó, Graziano Pesole, Tao Huang   +4 more
wiley   +1 more source

A Regulatory Role of NAD Redox Status on Flavin Cofactor Homeostasis in S. cerevisiae Mitochondria

Oxidative Medicine and Cellular Longevity, Volume 2013, Issue 1, 2013., 2013
Flavin adenine dinucleotide (FAD) and nicotinamide adenine dinucleotide (NAD) are two redox cofactors of pivotal importance for mitochondrial functionality and cellular redox balance. Despite their relevance, the mechanism by which intramitochondrial NAD(H) and FAD levels are maintained remains quite unclear in Saccharomyces cerevisiae. We investigated
Teresa Anna Giancaspero, Vittoria Locato, Maria Barile, Cristina Mazzoni   +3 more
wiley   +1 more source

Bmoo FIBMP‐I: A New Fibrinogenolytic Metalloproteinase from Bothrops moojeni Snake Venom

International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
A new fibrinogenolytic metalloproteinase (Bmoo FIBMP‐I) was purified from Bothrops moojeni snake venom. This enzyme was isolated through a combination of three chromatographic steps (ion‐exchange, molecular exclusion, and affinity chromatography). Analyses by reverse phase chromatography, followed by mass spectrometry, showed the presence of enzyme ...
F. S. Torres, B. Rates, M. T. R. Gomes, C. E. Salas, A. M. C. Pimenta, F. Oliveira, M. M. Santoro, M. E. de Lima, A. Cruz, F. Ducancel, Y. N. Utkin   +10 more
wiley   +1 more source

Procedimiento para la caracterización socio psicológica de cuadros: caso de estudio en empresa biofarmacéutica

Revista Cubana de Administración Pública y Empresarial
La caracterización socio psicológica es un método que contribuye a identificar las características, preparación técnico-profesional, así como las perspectivas de desarrollo de los cuadros, posibilitando su mejor ubicación y desempeño en las ...
Bárbara Susana Sánchez Vignau, Mayra Salome Romero Naranjo, María de los Ángeles Linares Borrell, María del Carmen Morales Álvarez   +3 more
doaj   +1 more source

Financialization, (latent) promises of biotechnology and new industrial barriers: Some lessons for semi-industrialized countries [PDF]

, 2018
El objeto de este trabajo es el análisis de la nueva configuración de la industria farmacéutica mundial, con epicentro en Estados Unidos, en la que las revoluciones de la biología molecular y cambios institucionales mayores permiten el desarrollo de ...
Lavarello, Pablo Jose
core  

TNF/TNFR1 is a Key Regulator of Prolonged Fasting‐Induced Decrease in Adipose Tissue

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Fasting triggers an inflammatory response and increases sympathetic tone in white adipose tissue (WAT), promoting fat breakdown and tissue remodeling. Fasting sparks an inflammatory response that underpins the reduction in adipocyte size and WAT remodeling.
Amanda Carla Clemente de Oliveira, Adma Maciel Babêtto, Mariele Lino Silva, Larisse de Souza Barbosa Lacerda, Thiago de Souza Rodrigues, Marina Chaves de Oliveira, Christine Rouault, Emmanuel L. Gautier, André Gustavo Oliveira, Karine Clément, Mauro Martins Teixeira, Geneviève Marcelin, Adaliene Versiani Matos Ferreira   +12 more
wiley   +1 more source

Nanosuspensions: particle size reduction as tool to improve lipophilic drugs bioavailability [PDF]

, 2013
En los últimos años, las nanosuspensiones han sido objeto de numerosos estudios con el n de evaluar sus propiedades biofarmacéuticas, demostrando en muchos casos valiosas ventajas frente a las formulaciones utilizadas convencionalmente.
Gonzalez Vidal, Noelia Lujan, Palma, Santiago Daniel, Starkloff, Walter Javier   +2 more
core   +1 more source

INTENSIDAD TECNOLÓGICA EN EL CONTEXTO EMPRESARIAL CUBANO [PDF]

, 2022
The article aims to delve into the business technological intensity from various perspectives as a support for the procedure for the evaluation, classification and improvement of the degree of technological intensity in the Cuban business context.
de León García, Dariel, Delgado Fernández, Mercedes, Jiménez Valero, Bisleivys, Suarez Hernández, Jesús   +3 more
core   +3 more sources

Design and Preparation of Pharmaceutical Solid Dosage Forms of Benznidazole for the Treatment of Chagas Disease [PDF]

, 2013
INTRODUCCIÓN: En Argentina se emplea el benznidazol como terapéutica de primera línea para el tratamiento etiológico del Chagas. Desde su lanzamiento (hace más de 40 años), sólo se dispone de comprimidos convencionales de 100 mg; no se han ...
García, Mónica Cristina, Jimenez Kairuz, Alvaro Federico, Lamas, Maria Celina, Leonardi, Darío, Maggia, Norma Graciela, Orlandi, Silvina, Paredes, Alejandro Javier, Romañuk, Carolina Beatriz, Salomon, Claudio Javier, Tarragona, Sonia   +9 more
core   +1 more source