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Biofilm Formation and the Role of Efflux Pumps in ESKAPE Pathogens [PDF]

Microorganisms
Nosocomial infections caused by ESKAPE pathogens represent a significant burden to global health. These pathogens may exhibit multidrug resistance (MDR) mechanisms, of which mechanisms such as efflux pumps and biofilm formation are gaining significant ...
Sorenson T, Zack K, Joshi S.
europepmc   +2 more sources

Microbial Biofilm: A Review on Formation, Infection, Antibiotic Resistance, Control Measures, and Innovative Treatment

Microorganisms, 2023
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to nosocomial, chronic infections in clinical settings.
Satish Sharma, James Mohler, S. Mahajan, S. Schwartz, Liana Bruggemann, R. Aalinkeel   +5 more
semanticscholar   +1 more source

The impacts of biomineralization and oil contamination on the compressive strength of waste plastic-filled mortar

Scientific Reports, 2022
Researchers have made headway against challenges of increasing cement infrastructure and low plastic recycling rates by using waste plastic in cementitious materials.
Kylee Rux, Seth Kane, Michael Espinal, Cecily Ryan, Adrienne Phillips, Chelsea Heveran   +5 more
doaj   +1 more source

Pathogenesis of the Pseudomonas aeruginosa Biofilm: A Review

Pathogens, 2022
Pseudomonas aeruginosa is associated with several human infections, mainly related to healthcare services. In the hospital, it is associated with resistance to several antibiotics, which poses a great challenge to therapy.
F. Tuon, Leticia Ramos Dantas, P. Suss, Victoria Stadler Tasca Ribeiro   +3 more
semanticscholar   +1 more source

Subsurface hydrocarbon degradation strategies in low- and high-sulfate coal seam communities identified with activity-based metagenomics

npj Biofilms and Microbiomes, 2022
Environmentally relevant metagenomes and BONCAT-FACS derived translationally active metagenomes from Powder River Basin coal seams were investigated to elucidate potential genes and functional groups involved in hydrocarbon degradation to methane in coal
Hannah D. Schweitzer, Heidi J. Smith, Elliott P. Barnhart, Luke J. McKay, Robin Gerlach, Alfred B. Cunningham, Rex R. Malmstrom, Danielle Goudeau, Matthew W. Fields   +8 more
doaj   +1 more source

Elucidation of health risks using metataxonomic and antibiotic resistance profiles of microbes in flood affected waterbodies, Kerala 2018

Journal of Flood Risk Management, 2021
The floods of 2018 caused havoc in the State of Kerala, situated in the extreme south‐west of India, in terms of infrastructure and health. This research article provides the first‐ever assessment of the bacterial diversity and its antibiotic ...
Aparna Shankar, Devika Jagajeedas, Megha Periyappilly Radhakrishnan, Merin Paul, Lekshmi Narendrakumar, Karthika Suryaletha, Velappan Savithri Akhila, Sudha Babu Nair, Sabu Thomas   +8 more
doaj   +1 more source

Single-Cell Infection of Influenza A Virus Using Drop-Based Microfluidics

Microbiology Spectrum, 2022
Drop-based microfluidics has revolutionized single-cell studies and can be applied toward analyzing tens of thousands to millions of single cells and their products contained within picoliter-sized drops.
Emma Kate Loveday, Humberto S. Sanchez, Mallory M. Thomas, Connie B. Chang   +3 more
doaj   +1 more source

Molecular Docking Study of the C-10 Massoia Lactone Compound as an Antimicrobial and Antibiofilm Agent against Candida tropicalis

The Scientific World Journal, 2023
Antimicrobial resistance is now considered a global health problem because it reduces the effectiveness of antimicrobial drugs. According to the World Health Organization (WHO), the highest mortality rate is associated with infections caused by multidrug-
Hasyrul Hamzah, Titik Nuryastuti, Widya Rahmah, Lutfi Chabib, Eka Siswanto Syamsul, Dwi Lestari, Asriullah Jabbar, Sylvia Utami Tunjung Pratiwi   +7 more
doaj   +1 more source

In Silico Analysis of Functionalized Hydrocarbon Production Using Ehrlich Pathway and Fatty Acid Derivatives in an Endophytic Fungus

Journal of Fungi, 2021
Functionalized hydrocarbons have various ecological and industrial uses, from signaling molecules and antifungal/antibacterial agents to fuels and specialty chemicals.
Kristopher A. Hunt, Natasha D. Mallette, Brent M. Peyton, Ross P. Carlson   +3 more
doaj   +1 more source

Combination effects of DNase I and tobramycin on survival and biofilm architectures of Pseudomonas aeruginosa and Klebsiella pneumoniae isolated from chronic rhinosinusitis patients [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2022
This study aimed to investigate the effects of DNase I in combination with tobramycin (TOB) on drug susceptibility and biofilm architectures of Pseudomonas aeruginosa and Klebsiella pneumoniae.
Chitchanok Anutrakunchai, Saharut Wongkaewkhiaw, Sakawrat Kanthawong, Sorujsiri Chareonsudjai, Rattiyaphorn Pakkulnan, Suwimol Taweechaisupapong   +5 more
doaj   +1 more source