Results 281 to 290 of about 678,915 (383)

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Microbial Distribution and Biofilm-Forming Capacity in the Reproductive Tract of Farm Ruminants. [PDF]

Animals (Basel)
So-In C, Piamalung N, Kongkaew A, Sriarun P, Kammungkun B, Phongchaiwasin S, Somwaeng B, Haputon W, Wadmuang T, Khankhum S, Sunthamala N.   +10 more
europepmc   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

Fatty Acids as Prebiotics and Their Role in Antibiofilm Activity. [PDF]

Antibiotics (Basel)
Nazzaro F, Coppola F, Fratianni F, Coppola R.   +3 more
europepmc   +1 more source

Novel polymer coatings prepared via layer-by-layer inhibit the formation of microbial biofilms

, 2021
Suelen P. Facchi
openalex   +1 more source

18S-V9 DNA metabarcoding detects the effect of water-quality impairment on stream biofilm eukaryotic assemblages

, 2020
Alison Minerovic, Marina Potapova, Christopher M. Sales, Jacob Price, Mihaela Enache   +4 more
openalex   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

In-vitro evaluation of the effectiveness of various disinfection procedures in reducing biofilm formation on customized implant abutments of different designs. [PDF]

Sci Rep
Özer NE, Niran B, Çalı A, Şahin Z.
europepmc   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Efficacy of Chlorine, QAC, and UV-C Light Against <i>Listeria monocytogenes</i> Biofilms on Food Contact Surfaces. [PDF]

Foods
Thapaliya M, Losso JN, Adhikari A.
europepmc   +1 more source