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Economic significance of biofilms: a multidisciplinary and cross-sectoral challenge
The increasing awareness of the significance of microbial biofilms across different sectors is continuously revealing new areas of opportunity in the development of innovative technologies in translational research, which can address their detrimental ...
Miguel Cámara +8 more
doaj +2 more sources
In the present research work, we addressed the changes in skin by which deep eutectic solvents (DES) enhanced transdermal permeation of bioactive compounds and propose a rationale for this mechanism. Several studies showed that these unusual liquids were
Rodrigo Boscariol +6 more
doaj +1 more source
Horizontal Gene Transfer of Antibiotic Resistance Genes in Biofilms
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it hinders the treatment of infections with antibiotics due to the ...
C. Michaelis, E. Grohmann
semanticscholar +1 more source
Translational challenges and opportunities in biofilm science: a BRIEF for the future
Biofilms are increasingly recognised as a critical global issue in a multitude of industries impacting health, food and water security, marine sector, and industrial processes resulting in estimated economic cost of $5 trillion USD annually.
C. J. Highmore +8 more
doaj +1 more source
Understanding bacterial biofilms: From definition to treatment strategies
Bacterial biofilms are complex microbial communities encased in extracellular polymeric substances. Their formation is a multi-step process. Biofilms are a significant problem in treating bacterial infections and are one of the main reasons for the ...
Ailing Zhao, Jia-Zheng Sun, Yipin Liu
semanticscholar +1 more source
Many skin disorders, including cancer, have inflammatory components. The non-invasive detection of related biomarkers could therefore be highly valuable for both diagnosis and follow up on the effect of treatment.
Maxim Morin +3 more
doaj +1 more source
E. coli is one of the etiological agents responsible for pyometra in female dogs, with conventional treatment involving ovariohysterectomy. Here, we report the isolation and full characterization of two novel lytic phages, viz.
Victor M. Balcão +8 more
doaj +1 more source
Strategy to combat biofilms: a focus on biofilm dispersal enzymes
Bacterial biofilms, which consist of three-dimensional extracellular polymeric substance (EPS), not only function as signaling networks, provide nutritional support, and facilitate surface adhesion, but also serve as a protective shield for the residing ...
Shaochi Wang +6 more
semanticscholar +1 more source
Transdermal Permeation Assays of Curcumin Aided by CAGE-IL: In Vivo Control of Psoriasis
Psoriasis is a clinically heterogeneous skin disease with an important genetic component, whose pathophysiology is not yet fully understood and for which there is still no cure.
Rodrigo Boscariol +6 more
doaj +1 more source
Biofilms: Formation, drug resistance and alternatives to conventional approaches
Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-spectrum antibiotics in their typical concentrations or even in higher doses.
Ruba Mirghani +13 more
semanticscholar +1 more source

