Results 1 to 10 of about 213,251 (165)

Mutations in hik26 and slr1916 lead to high-light stress tolerance in Synechocystis sp. PCC6803

Communications Biology, 2021
In this paper, the authors investigated the high light stress response in Synechocystis sp. PCC6803 and revealed two key mutations in hik26 and slr1916 using whole genome sequencing and reverse engineering.
Katsunori Yoshikawa, Kenichi Ogawa, Yoshihiro Toya, Seiji Akimoto, Fumio Matsuda, Hiroshi Shimizu   +5 more
doaj   +1 more source

Downregulated Expression of CLEC9A as Novel Biomarkers for Lung Adenocarcinoma

Frontiers in Oncology, 2021
PurposeAbnormal CLEC9A expression is concerned with carcinogenesis. However, the role of CLEC9A in lung adenocarcinoma (LUAD) remains unknown. The goal of this study was to reveal the role of CLEC9A in LUAD based on bioinformatics and cellular functional
Fang Miao, Zhiguo Lou, Shuhua Ji, Dan Wang, Yaolan Sun, Huan Liu, Chenggang Yang, Chenggang Yang   +7 more
doaj   +1 more source

Novel enhancer mediates the RPL36A-HNRNPH2 readthrough loci and GLA gene expressions associated with fabry disease

Frontiers in Genetics, 2023
Fabry disease (FD) is a rare genetic condition caused by mutations in the GLA gene, located on the X chromosome in the RPL36-HNRNPH2 readthrough genomic region. This gene produces an enzyme called alpha-galactosidase A (α-Gal A). When the enzyme does not
Mohammed A. Al-Obaide, Saimul Islam, Ibtisam Al-Obaidi, Tetyana L. Vasylyeva   +3 more
doaj   +1 more source

Crowdsourcing for bioinformatics [PDF]

Bioinformatics, 2013
Abstract Motivation: Bioinformatics is faced with a variety of problems that require human involvement. Tasks like genome annotation, image analysis, knowledge-base population and protein structure determination all benefit from human input.
Benjamin M. Good, Andrew I. Su
openaire   +3 more sources

In silico analysis of CDC73 gene revealing 11 novel SNPs with possible association to Hyperparathyroidism-Jaw Tumor syndrome

The EuroBiotech Journal, 2020
Hyperparathyroidism-Jaw Tumor (HPT-JT) is an autosomal dominant disorder with variable expression, with an estimated prevalence of 6.7 per 1,000 population.
Abdelmoneim Abdelrahman H., Mohammed Alaa I., Gadim Esraa O., Mohammed Mayada Alhibir, Hamza Sara H., Mirghani Sara A., Mahmoud Thwayba A., Hassan Mohamed A.   +7 more
doaj   +1 more source

Computational profiling and prognostic modeling based on lysosome-related genes in colorectal cancer

Frontiers in Genetics, 2023
Background: Despite significant advances over the past decade, patients diagnosed with advanced colorectal cancer (CRC) continue to face unfavorable prognoses.
Linjie Zhang, Linjie Zhang, Jingbang Yang, Jingbang Yang, Yizhang Deng, Yizhang Deng, Wuguo Deng, Liren Li, Liren Li   +8 more
doaj   +1 more source

Bioinformatics-Based Analysis of Key Genes in Steroid-Induced Osteonecrosis of the Femoral Head That Are Associated with Copper Metabolism

Biomedicines, 2023
Osteonecrosis of the femoral head (ONFH) is a common disabling disease. Copper has positive effects on cells that regulate bone metabolism. However, the relationship between copper metabolism (CM) and steroid-induced ONFH (SONFH) remains unclear.
Baochuang Qi, Chuan Li, Xingbo Cai, Luqiao Pu, Minzheng Guo, Zhifang Tang, Pengfei Bu, Yongqing Xu   +7 more
doaj   +1 more source

Sensorless Driving/Braking Control for Electric Vehicles

Actuators, 2020
A sensorless driving/braking control system for electric vehicles is explained in the present paper. In the proposed system, a field-oriented control (FOC) was used to integrate driving and braking controls in a unified module for reducing the cost of ...
En-Ping Chen, Jiangfeng Cheng, Jia-Hung Tu, Chun-Liang Lin   +3 more
doaj   +1 more source

Identification of key genes and pathways in chronic rhinosinusitis with nasal polyps and asthma comorbidity using bioinformatics approaches

Frontiers in Immunology, 2022
Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma comorbidity (ACRSwNP) present severe symptoms and are more likely to relapse. However, the pathogenesis of ACRSwNP is not fully understood.
Mingming Wang, Shuangmei Tang, Xiaoqi Yang, Xinyu Xie, Yang Luo, Shaojuan He, Xuezhong Li, Xin Feng   +7 more
doaj   +1 more source

Chemistry in Bioinformatics [PDF]

BMC Bioinformatics, 2005
Abstract Abstract Chemical information is now seen as critical for most areas of life sciences. But unlike Bioinformatics, where data is openly available and freely re-usable, most chemical information is closed and cannot be re-distributed without permission.
Peter Murray-Rust, John B. O. Mitchell, Henry S. Rzepa   +2 more
openaire   +6 more sources