Results 91 to 100 of about 251,008 (313)
Bioinformatics for immunologists [PDF]
Immunology, 2018 SummaryImmunology was once a specialty prone to cause dismay or even scepticism among outsiders for its struggles to visualize poorly understood, complex interactions through descriptive models integrating cell types, their factors and functions. This was the age of ‘too many soft ideas propped up by too little hard data’.
openaire +2 more sources
Bioscientists, libraries and bioinformatic resources
, 2014 Bioinformatics is an interdisciplinary scientific subject which connects biology, biomedicine and information science. Bioinformatics generates new biological knowledge by using computer methods and biological databases and can thereby play an important ...
Wickenberg, Maria
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Frontiers in GeneticsBackgroundNeutrophil extracellular traps (NETs) cause delayed wound closed up in type 2 diabetes mellitus (T2DM), but the specific regulatory mechanism of NETs-related genes (NETs-RGs) in T2DM is unclear.MethodsWe acquired GSE21321 and GSE15932 datasets ...
Meifang He +3 more
doaj +1 more source
Open Life Sciences, 2019 The WRKY gene family is an ancient plant transcription factor (TF) family with a vital role in plant growth and development, especially in response to biotic and abiotic stresses. Although many researchers have studied WRKY TFs in numerous plant species,
He Xia +4 more
doaj +1 more source
Detailed laboratory and bioinformatic methods
, 2019 These detailed laboratory and bioinformatic methods for the creation of a Hermes insertion library in fission yeast, and processing of the sequencing files.Extracted from the PhD thesis of Leanne Grech.
Daniel Jeffares (649018) +1 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Promising Potential of Lonchocarpus utilis against South American Myasis
Plants, 2019 Traditional medicine is especially important in the treatment of neglected tropical diseases because it is the way the majority of populations of affected countries manage primary healthcare.
Carmen X. Luzuriaga-Quichimbo +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Characterization of the function and clinical value of ERCC family genes in lung adenocarcinoma
Frontiers in OncologyIntroductionERCC genes, responsible for encoding enzymes involved in base excision repair, have been implicated in various cancers, contributing to chemoresistance.
Zhimin Lu, Guoxin Hou
doaj +1 more source