ARG-ANNOT, a New Bioinformatic Tool To Discover Antibiotic Resistance Genes in Bacterial Genomes
Antimicrobial Agents and Chemotherapy, 2013 ARG-ANNOT (Antibiotic Resistance Gene-ANNOTation) is a new bioinformatic tool that was created to detect existing and putative new antibiotic resistance (AR) genes in bacterial genomes.
Sushim K Gupta +6 more
semanticscholar +1 more source
Adaptation by stochastic switching of a monostable genetic circuit in Escherichia coli
Molecular Systems Biology, 2011 Stochastic switching is considered as a cost‐saving strategy for adaptation to environmental challenges. We show here that stochastic switching of a monostable circuit can mediate the adaptation of the engineered OSU12‐hisC Escherichia coli strain to ...
Saburo Tsuru +8 more
doaj +1 more source
Relationship Between the Pyroptosis Pathway and Epilepsy: A Bioinformatic Analysis
Frontiers in Neurology, 2022 PurposeThis study aimed to analyse the correlation between the pyroptosis pathway and epilepsy using bioinformatics analysis technology. We analyzed the expression of gasdermin D (GSDMD) and gasdermin E (GSDME), the key molecules of pyroptosis, in kainic
Lu Xia +5 more
doaj +1 more source
Supplementary methods for IPAM and buoyant weight, relative risk analysis, 16S library preparation, transcriptomic pre-processing bioinformatic pipeline, 16S rRNA pre-processing bioinformatic pipeline. [PDF]
, 2023 Supplementary methods for IPAM and buoyant weight, relative risk analysis, 16S library preparation, transcriptomic pre-processing bioinformatic pipeline, 16S rRNA pre-processing bioinformatic pipeline.
Amelia Moura (11552319) +7 more
core +1 more source
Detecting circular RNAs: bioinformatic and experimental challenges
Nature reviews genetics, 2016 The pervasive expression of circular RNAs (circRNAs) is a recently discovered feature of gene expression in highly diverged eukaryotes. Numerous algorithms that are used to detect genome-wide circRNA expression from RNA sequencing (RNA-seq) data have ...
L. Szabo, J. Salzman
semanticscholar +1 more source
The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines [PDF]
, 2014 The hexameric MCM complex is the catalytic core of the replicative helicase in eukaryotic and archaeal cells. Here we describe the first in vivo analysis of archaeal MCM protein structure and function relationships using the genetically tractable ...
Tatjana P Kristensen +12 more
core +1 more source
Bioinformatic analysis of maize gene encoding starch branching enzyme SBEIIb.
Plant Varieties Studying and Protection, 2016 Purpose. Investigation of maize ae1 gene polymorphism by bioinformatic methods. Methods. Global and local alignment of the nucleotide and amino acid sequences, in silico translation and transcription, translates modeling, primers design, phylogenetic ...
Г. І. Сліщук +2 more
doaj +1 more source
biomisc_R: command line bioinformatic scripts written in R [PDF]
, 2021 command line bioinformatic scripts written in
Olga Tsiouri
core +1 more source
Computational and Structural Biotechnology JournalIn recent years, the role of bioinformatics and computational biology together with omics techniques and transcriptomics has gained tremendous importance in biomedicine and healthcare, particularly for the identification of biomarkers for precision ...
Diletta Rosati +6 more
semanticscholar +1 more source
Journal of Extracellular VesiclesExtracellular vesicles (EVs) are heterogeneous entities secreted by cells into their microenvironment and systemic circulation. Circulating EVs carry functional small RNAs and other molecular footprints from their cell of origin, and thus have evident ...
Rebecca T. Miceli +16 more
semanticscholar +1 more source