Results 41 to 50 of about 273,667 (297)

The schematic representation of bioinformatic analysis.

open access: yes, 2023
The schematic representation of bioinformatic analysis.
Ning Zhang (23771)   +6 more
core   +1 more source

Adaptation by stochastic switching of a monostable genetic circuit in Escherichia coli

open access: yesMolecular Systems Biology, 2011
Stochastic switching is considered as a cost‐saving strategy for adaptation to environmental challenges. We show here that stochastic switching of a monostable circuit can mediate the adaptation of the engineered OSU12‐hisC Escherichia coli strain to ...
Saburo Tsuru   +8 more
doaj   +1 more source

Relationship Between the Pyroptosis Pathway and Epilepsy: A Bioinformatic Analysis

open access: yesFrontiers in Neurology, 2022
PurposeThis study aimed to analyse the correlation between the pyroptosis pathway and epilepsy using bioinformatics analysis technology. We analyzed the expression of gasdermin D (GSDMD) and gasdermin E (GSDME), the key molecules of pyroptosis, in kainic
Lu Xia   +5 more
doaj   +1 more source

Bioinformatic analysis of maize gene encoding starch branching enzyme SBEIIb.

open access: yesPlant Varieties Studying and Protection, 2016
Purpose. Investigation of maize ae1 gene polymorphism by bioinformatic methods. Methods. Global and local alignment of the nucleotide and amino acid sequences, in silico translation and transcription, translates modeling, pri­mers design, phylogenetic ...
Г. І. Сліщук   +2 more
doaj   +1 more source

Diagram-of-bioinformatic-pipelines

open access: yes, 2012
Diagram-of-bioinformatic ...
Bodles, William   +13 more
core   +1 more source

Bioscientists, libraries and bioinformatic resources

open access: yes, 2014
Bioinformatics is an interdisciplinary scientific subject which connects biology, biomedicine and information science. Bioinformatics generates new biological knowledge by using computer methods and biological databases and can thereby play an important ...
Wickenberg, Maria
core   +2 more sources

The Clinical Significance and Transcription Regulation of a DNA Damage Repair Gene, SMC4, in Low-Grade Glioma via Integrated Bioinformatic Analysis

open access: yesFrontiers in Oncology, 2021
Glioma is the most common type of malignant tumor in the central nervous system with an unfavorable prognosis and limited treatment. In this study, we are devoted to addressing the prognostic value of DNA damage repair-related genes in low-grade glioma ...
Yan Wang, Zhisheng Wu
doaj   +1 more source

Microsatellite density landscapes illustrate short tandem repeats aggregation in the complete reference human genome

open access: yesBMC Genomics
Background Microsatellites are increasingly realized to have biological significance in human genome and health in past decades, the assembled complete reference sequence of human genome T2T-CHM13 brought great help for a comprehensive study of short ...
Yun Xia   +27 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A novel Cuprotosis-related signature predicts the prognosis and selects personal treatments for melanoma based on bioinformatics analysis

open access: yesFrontiers in Oncology, 2023
BackgroundMelanoma is a common and aggressive cutaneous malignancy characterized by poor prognosis and a high fatality rate. Recently, due to the application of Immune–checkpoint inhibitors (ICI) in melanoma treatment, melanoma patients’ prognosis has ...
Bingqian Hu   +5 more
doaj   +1 more source

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