Results 91 to 100 of about 257,337 (308)

Identification and validation of diagnostic genes associated with neutrophil extracellular traps of type 2 diabetes mellitus

open access: yesFrontiers in Genetics
BackgroundNeutrophil extracellular traps (NETs) cause delayed wound closed up in type 2 diabetes mellitus (T2DM), but the specific regulatory mechanism of NETs-related genes (NETs-RGs) in T2DM is unclear.MethodsWe acquired GSE21321 and GSE15932 datasets ...
Meifang He   +3 more
doaj   +1 more source

Genome-wide analysis of the WRKY gene family and its response to abiotic stress in buckwheat (Fagopyrum tataricum)

open access: yesOpen Life Sciences, 2019
The WRKY gene family is an ancient plant transcription factor (TF) family with a vital role in plant growth and development, especially in response to biotic and abiotic stresses. Although many researchers have studied WRKY TFs in numerous plant species,
He Xia   +4 more
doaj   +1 more source

Is “bioinformatics” dead?

open access: yesPLOS Biology, 2021
Why would a computational biologist with 40 years of research experience say bioinformatics is dead? The short answer is, in being the Founding Dean of a new School of Data Science, what we do suddenly looks different.
openaire   +4 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Promising Potential of Lonchocarpus utilis against South American Myasis

open access: yesPlants, 2019
Traditional medicine is especially important in the treatment of neglected tropical diseases because it is the way the majority of populations of affected countries manage primary healthcare.
Carmen X. Luzuriaga-Quichimbo   +4 more
doaj   +1 more source

Bioinformatic data sets and consensus Kozak sequences.

open access: yes, 2014
Bioinformatic data sets and consensus Kozak sequences.
Amy Robbins (633039)   +4 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Characterization of the function and clinical value of ERCC family genes in lung adenocarcinoma

open access: yesFrontiers in Oncology
IntroductionERCC genes, responsible for encoding enzymes involved in base excision repair, have been implicated in various cancers, contributing to chemoresistance.
Zhimin Lu, Guoxin Hou
doaj   +1 more source

Detailed laboratory and bioinformatic methods

open access: yes, 2019
These detailed laboratory and bioinformatic methods for the creation of a Hermes insertion library in fission yeast, and processing of the sequencing files.Extracted from the PhD thesis of Leanne Grech.
Daniel Jeffares (649018)   +1 more
core   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

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