Results 171 to 180 of about 251,008 (313)

Erratum to "Bioinformatic Analysis to Identify Biomarker Candidates of Complex Karyotype Soft Tissue Sarcomas with <i>CDK4</i>-Amplification" [Biomol Ther 34(2), 379-390 (2026)]. [PDF]

Biomol Ther (Seoul)
Lee EY, Cho HS, Kim JH, Kang HG, Park JW, Cho A, You HJ.   +6 more
europepmc   +1 more source

Bioinformatic analysis of metabarcoding data using DADA2 - Theoretical part

The presentation, delivered during the BIOLAWEB Virtual Training in May-June 2024, provides a comprehensive theoretical foundation for understanding bioinformatic workflows in DNA metabarcoding.BIOLAWEB Virtual training - Bioinformatic (May-June ...
Lemonnier, Clarisse
core  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Novel Disease-Specific Panel of Salivary microRNAs for the Detection of Oral Squamous Cell Carcinoma from Early Invasion to Stage IV Disease. [PDF]

Int J Mol Sci
Gintoni I, Vassiliou S, Kardara Bellou M, Balakas A, Lefantzis N, Papakosta V, Vlachakis D, Chrousos GP, Yapijakis C.   +8 more
europepmc   +1 more source

Bioinformatic Pipeline Scripts Amplicon Sequencing - Grey Box Grassy Woodlands

<p dir="ltr">Bioinformatic scripts for the paper titled "Habitat fragmentation shifts soil microbial composition but not richness". Scripts outline the bioinformatic pipeline using DADA2 and QIIME2 to create amplicon sequence variant tables from ...

core   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Rapid identification of microbial pathogens and antimicrobial resistance from bloodstream infections using long-read sequencing. [PDF]

Microb Genom
Lerminiaux N, Fakharuddin K, Adam HJ, Bharat A, Golding GR, Martin I, Mulvey M, Mataseje LF.   +7 more
europepmc   +1 more source

The growth of bioinformatics [PDF]

Briefings in Bioinformatics, 2006
openaire   +2 more sources

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source

Bioinformatic Resistome Profiling of Metal Tolerance Mechanisms in Endodontic Infections: Implications for Antimicrobial Nanoparticle-Based Biomaterials. [PDF]

J Funct Biomater
Luna-Lara CA, Luna-Dominguez CR, Oliver-Parra R, Criollo-Barrios OV, Vaca-Jasso MLD, Salas-Orozco MF.   +5 more
europepmc   +1 more source