Results 101 to 110 of about 272,032 (296)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Flowchart for the process of bioinformatic analysis.

open access: yes, 2015
Flowchart for the process of bioinformatic analysis.
Xiaoming Wei (191334)   +11 more
core   +1 more source

Supplementary methods for IPAM and buoyant weight, relative risk analysis, 16S library preparation, transcriptomic pre-processing bioinformatic pipeline, 16S rRNA pre-processing bioinformatic pipeline.

open access: yes, 2023
Supplementary methods for IPAM and buoyant weight, relative risk analysis, 16S library preparation, transcriptomic pre-processing bioinformatic pipeline, 16S rRNA pre-processing bioinformatic pipeline.
Amelia Moura (11552319)   +7 more
core   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Bioinformatic pipeline followed for annotation of unigenes.

open access: yes, 2013
Bioinformatic pipeline followed for annotation of unigenes.
Nisha Joy (384872)   +3 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Bioinformatic data sets and consensus Kozak sequences.

open access: yes, 2014
Bioinformatic data sets and consensus Kozak sequences.
Amy Robbins (633039)   +4 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Detailed laboratory and bioinformatic methods

open access: yes, 2019
These detailed laboratory and bioinformatic methods for the creation of a Hermes insertion library in fission yeast, and processing of the sequencing files.Extracted from the PhD thesis of Leanne Grech.
Daniel Jeffares (649018)   +1 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

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