Results 101 to 110 of about 1,477,984 (353)
Shouji: A Fast and Efficient Pre-Alignment Filter for Sequence Alignment
, 2019 Motivation: The ability to generate massive amounts of sequencing data continues to overwhelm the processing capability of existing algorithms and compute infrastructures.
Alkan, Can +4 more
core +2 more sources
A new bioinformatics analysis tools framework at EMBL–EBI
Nucleic Acids Res., 2010 The EMBL-EBI provides access to various mainstream sequence analysis applications. These include sequence similarity search services such as BLAST, FASTA, InterProScan and multiple sequence alignment tools such as ClustalW, T-Coffee and MUSCLE.
Mickael Goujon +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
The application of bioinformatics on academic thesis of Chinese graduate student: a bibliometric analysis base on VOSviewer [PDF]
Yixue xinzhi zazhiObjective To analyze the application status of bioinformatics on Chinese medical graduate students.Methods Available academic thesis was filtered with a topic of bioinformatics medical research ranging from 2003 January 1st to 2023 December 31st in CNKI ...
LIU Junli +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Identification of the LNC02362–EFNA5 axis as a Potential Prognosis Biomarker in Hepatocellular Carcinoma via Comprehensive Bioinformatics Analysis [PDF]
, 2023 Yuan Liu +14 more
openalex +1 more source
Perseus: A Bioinformatics Platform for Integrative Analysis of Proteomics Data in Cancer Research.
Methods in molecular biology, 2018 Mass spectrometry-based proteomics is a continuously growing field marked by technological and methodological improvements. Cancer proteomics is aimed at pursuing goals such as accurate diagnosis, patient stratification, and biomarker discovery, relying ...
Stefka Tyanova, Jüergen Cox
semanticscholar +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
JPBI (Jurnal Pendidikan Biologi Indonesia)Plant metabolite compounds have been applied on plant cellular metabolism, produces organic and inorganic compounds, primary and secondary bioactive molecules, such as glucose, amino acids, fat acids, alkaloids, flavonoids, and terpenoids. Undergraduate
Risanti Dhaniaputri +2 more
doaj +1 more source