Results 101 to 110 of about 1,268,351 (323)

Cloud Bioinformatics in a private cloud deployment

open access: yes, 2013
This chapter describes service portability for a private cloud deployment, including a detailed case study about Cloud Bioinformatics services developed as part of the Cloud Computing Adoption Framework (CCAF).
Chang, Victor
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Multidisciplinary teaching of Biotechnology and Omics sciences [PDF]

open access: yes, 2017
In the last years, there was a great boom in the Omics fields that have developed as multidisciplinary sciences. They use laboratory techniques related to Biology and Chemistry but also Bioinformatics tools. However, the developmental progress of these
Canovas-Ramos, Francisco Miguel   +6 more
core  

RD-Connect: An Integrated Platform Connecting Databases, Registries, Biobanks and Clinical Bioinformatics for Rare Disease Research [PDF]

open access: hybrid, 2014
Rachel Thompson   +18 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The PDTIS bioinformatics platform: from sequence to function - DOI: 10.3395/reciis.v1i2.Sup.98en

open access: yesRECIIS, 2007
Since the eighties, Bioinformatics has acquired a growing importance in the biological sciences. Due to the complexity of hardware and software tools, and the need for a specialized management of network infrastructure, data processing and storage, many ...
Thomas Dan Otto   +3 more
doaj  

SMaSH: A Benchmarking Toolkit for Human Genome Variant Calling

open access: yes, 2014
Motivation: Computational methods are essential to extract actionable information from raw sequencing data, and to thus fulfill the promise of next-generation sequencing technology. Unfortunately, computational tools developed to call variants from human
Bresler, Ma'ayan   +9 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Immortal Mortals [PDF]

open access: yes, 2015
Junior Information Systems and Bioinformatics major Michael Kiflezghi focuses his research interests on an organism’s lifespan and gut microbial ...
Giles, Sterling
core   +1 more source

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