Results 81 to 90 of about 1,289,019 (331)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Bioinformatics Software Engineering
Journal of Statistical Software, 2005 s not available for ...
Robert Gentleman
doaj +1 more source
PLoS ONE, 2021 As powerful computational tools and 'big data' transform the biological sciences, bioinformatics training is becoming necessary to prepare the next generation of life scientists. Furthermore, because the tools and resources employed in bioinformatics are
Adam J Kleinschmit +12 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2015 Junior Information Systems and Bioinformatics major Michael Kiflezghi focuses his research interests on an organism’s lifespan and gut microbial ...
Giles, Sterling
core +1 more source
The Penna Model of Biological Aging
, 2007 This review deals with computer simulation of biological ageing, particularly with the Penna model of 1995.Comment: 16-page invited review submitted to Bioinformatics and Biology ...
Stauffer, D.
core +3 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The application of bioinformatics on academic thesis of Chinese graduate student: a bibliometric analysis base on VOSviewer [PDF]
Yixue xinzhi zazhiObjective To analyze the application status of bioinformatics on Chinese medical graduate students.Methods Available academic thesis was filtered with a topic of bioinformatics medical research ranging from 2003 January 1st to 2023 December 31st in CNKI ...
LIU Junli +4 more
doaj +1 more source
Bayesian regularization of hidden Markov models with an application to bioinformatics [PDF]
, 2000 This paper discusses a Bayesian approach to regularizing hidden Markov models and demonstrates an application of this scheme to ...
Husmeier, D.
core
Shouji: A Fast and Efficient Pre-Alignment Filter for Sequence Alignment
, 2019 Motivation: The ability to generate massive amounts of sequencing data continues to overwhelm the processing capability of existing algorithms and compute infrastructures.
Alkan, Can +4 more
core +2 more sources