Results 81 to 90 of about 840,775 (293)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The application of bioinformatics on academic thesis of Chinese graduate student: a bibliometric analysis base on VOSviewer [PDF]

Yixue xinzhi zazhi
Objective To analyze the application status of bioinformatics on Chinese medical graduate students.Methods Available academic thesis was filtered with a topic of bioinformatics medical research ranging from 2003 January 1st to 2023 December 31st in CNKI ...
LIU Junli, JI Ziyi, LYU Jinyu, CUI Yiming, HONG Jian   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Provenance of e-Science Experiments - experience from Bioinformatics

, 2003
Like experiments performed at a laboratory bench, the data associated with an e-Science experiment are of reduced value if other scientists are not able to identify the origin, or provenance, of those data.
Stevens, R, Watson, P, Zhao, J, Moreau, L, Moreau, Luc, Marvin, Darren, Marvin, D, Addis, Matthew, Addis, M, Zhao, Jun, Greenwood, Mark, Greenwood, M, Goble, Carole, Oinn, Tom, Stevens, Robert, Goble, C, Oinn, T   +16 more
core   +1 more source

Causal Relationships Between Leukocyte Subsets and Adverse Fetal Outcomes: A Mendelian Randomization Study

Mediators of Inflammation
Conclusions: This study provided profound insights into the intricate regulatory mechanisms of leukocyte subsets in neonatal diseases, paving the way for new avenues in the diagnosis and treatment of associated disorders.
Hong Chen, Li-Zhen Shao, Ying-Xiong Wang, Zhi-Jie Han, Yong-Heng Wang, Xia Li, Jing-Yu Chen, Tai-Hang Liu   +7 more
doaj   +1 more source

Bioinformatics core competencies for undergraduate life sciences education.

PLoS ONE, 2018
Although bioinformatics is becoming increasingly central to research in the life sciences, bioinformatics skills and knowledge are not well integrated into undergraduate biology education. This curricular gap prevents biology students from harnessing the
Melissa A Wilson Sayres, Charles Hauser, Michael Sierk, Srebrenka Robic, Anne G Rosenwald, Todd M Smith, Eric W Triplett, Jason J Williams, Elizabeth Dinsdale, William R Morgan, James M Burnette, Samuel S Donovan, Jennifer C Drew, Sarah C R Elgin, Edison R Fowlks, Sebastian Galindo-Gonzalez, Anya L Goodman, Nealy F Grandgenett, Carlos C Goller, John R Jungck, Jeffrey D Newman, William Pearson, Elizabeth F Ryder, Rafael Tosado-Acevedo, William Tapprich, Tammy C Tobin, Arlín Toro-Martínez, Lonnie R Welch, Robin Wright, Lindsay Barone, David Ebenbach, Mindy McWilliams, Kimberly C Olney, Mark A Pauley   +33 more
doaj   +1 more source

Bioinformatics Software Engineering

Journal of Statistical Software, 2005
s not available for ...
Robert Gentleman
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Awareness and Predictors of the Use of Bioinformatics in Genome Research in Saudi Arabia

International Journal of General Medicine, 2023
Lamya Alomair,1,2 Mostafa A Abolfotouh2,3 1AI and Bioinformatics Department, King Abdullah International Medical Research Center (KAIMRC), Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia; 2King Saud Bin-Abdulaziz University for Health ...
Alomair L, Abolfotouh MA
doaj  

Undergraduate Bioinformatics Workshops Provide Perceived Skills

Journal of Microbiology & Biology Education, 2014
Bioinformatics is becoming an important part of undergraduate curriculum, but expertise and well-evaluated teaching materials may not be available on every campus. Here, a guest speaker was utilized to introduce bioinformatics and web-available exercises
Robin Herlands Cresiski
doaj   +1 more source