Results 111 to 120 of about 1,243,490 (281)
Bayesian regularization of hidden Markov models with an application to bioinformatics [PDF]
, 2000 This paper discusses a Bayesian approach to regularizing hidden Markov models and demonstrates an application of this scheme to ...
Husmeier, D.
core
Identification and validation of key long non-coding RNAs in resveratrol protect against IL-1β-treated chondrocytes via integrated bioinformatic analysis [PDF]
, 2021 Hong Yi +5 more
openalex +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Undergraduate Bioinformatics Workshops Provide Perceived Skills
Journal of Microbiology & Biology Education, 2014 Bioinformatics is becoming an important part of undergraduate curriculum, but expertise and well-evaluated teaching materials may not be available on every campus. Here, a guest speaker was utilized to introduce bioinformatics and web-available exercises
Robin Herlands Cresiski
doaj +1 more source
khmer: Working with Big Data in Bioinformatics [PDF]
, 2013 We introduce design and optimization considerations for the 'khmer' package.Comment: Invited chapter for forthcoming book on Performance of Open Source ...
Brown, C. Titus, McDonald, Eric
core
Bioinformatic screening of human ESTs for differentially expressed genes in normal and tumor tissues [PDF]
, 2006 Abdel Aouacheria +4 more
openalex +1 more source
Molecular Oncology, EarlyView.In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa +14 more
wiley +1 more source
The PDTIS bioinformatics platform: from sequence to function - DOI: 10.3395/reciis.v1i2.Sup.98en
RECIIS, 2007 Since the eighties, Bioinformatics has acquired a growing importance in the biological sciences. Due to the complexity of hardware and software tools, and the need for a specialized management of network infrastructure, data processing and storage, many ...
Thomas Dan Otto +3 more
doaj
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source