Results 121 to 130 of about 1,337,095 (390)

Bioinformatics-Aided Venomics

open access: yesToxins, 2015
Venomics is a modern approach that combines transcriptomics and proteomics to explore the toxin content of venoms. This review will give an overview of computational approaches that have been created to classify and consolidate venomics data, as well as ...
Quentin Kaas, David J. Craik
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Cellular Automata and Its Applications in Bioinformatics: A Review [PDF]

open access: yesGlobal Perspectives on Artificial Intelligence (GPAI) Volume 2 Issue 2, Pages 16-22 April 2014, 2014
This paper aims at providing a survey on the problems that can be easily addressed by cellular automata in bioinformatics. Some of the authors have proposed algorithms for addressing some problems in bioinformatics but the application of cellular automata in bioinformatics is a virgin field in research.
arxiv  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Clonal-Based Cellular Automata in Bioinformatics [PDF]

open access: yesJournal of Advanced Research in Applied Artificial Intelligence & Neural Network Vol.1, Issue1, 2014, 2014
This paper aims at providing a survey on the problems that can be easily addressed by clonalbased cellular automata in bioinformatics. Researchers try to address the problems in bioinformatics independent of each problem. None of the researchers has tried to relate the major problems in bioinformatics and find a solution using common frame work.
arxiv  

Causal Relationships Between Leukocyte Subsets and Adverse Fetal Outcomes: A Mendelian Randomization Study

open access: yesMediators of Inflammation
Conclusions: This study provided profound insights into the intricate regulatory mechanisms of leukocyte subsets in neonatal diseases, paving the way for new avenues in the diagnosis and treatment of associated disorders.
Hong Chen   +7 more
doaj   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Generalized Centroid Estimators in Bioinformatics [PDF]

open access: yesPLoS ONE 6(2):e16450, 2011, 2013
In a number of estimation problems in bioinformatics, accuracy measures of the target problem are usually given, and it is important to design estimators that are suitable to those accuracy measures. However, there is often a discrepancy between an employed estimator and a given accuracy measure of the problem.
arxiv  

The Roots of Bioinformatics

open access: yesPLoS Computational Biology, 2010
Every new scientific discipline or methodology reaches a point in its maturation where it is fruitful for it to turn its gaze inward, as well as backward. Such introspection helps to clarify the essential structure of a field of study, facilitating communication, pedagogy, standardization, and the like, while retrospection aids this process by ...
openaire   +5 more sources

InCoB2012 Conference: from biological data to knowledge to technological breakthroughs

open access: yesBMC Bioinformatics, 2012
Ten years ago when Asia-Pacific Bioinformatics Network held the first International Conference on Bioinformatics (InCoB) in Bangkok its theme was North-South Networking. At that time InCoB aimed to provide biologists and bioinformatics researchers in the
Schönbach Christian   +5 more
doaj   +1 more source

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