Results 271 to 280 of about 1,268,351 (323)

Genome size estimation from long read overlaps. [PDF]

Bioinformatics
Hall MB, Zhou C, Coin LJM.
europepmc   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

A bioinformatics pipeline for Screening Nodule-specific Cysteine-Rich (NCR) like peptides from Trigonella foenum-graecum and Medicago truncatula genomes

Sneha Bidvi, Rajendra Choure, R.S. Jadhav, Manohar V. Padul, Sayli Mandavkar, Akshada Bhadane, Mrunal Posam   +6 more
openalex   +1 more source

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

Advanced Science, EarlyView.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou, Ling‐Feng Gu, Yi‐Xi Chen, Peng Jing, Tong‐Tong Yang, Ye He, Yu‐Lin Bao, Xiang‐Zheng Zhang, Chong Du, Si‐Bo Wang, Tian‐Kai Shan, Jia‐Yi Chen, Hao Wang, Qi‐Ming Wang, Li‐Ping Xie, Yang Zhao, Yong Ji, Lian‐Sheng Wang   +17 more
wiley   +1 more source

BIWT: a bioinformatics walkthrough for embedding spatial multiomics in agent-based models for virtual cells. [PDF]

Bioinformatics
Bergman DR, Johnson JAI, Naji M, Booth M, Lima da Rocha H, Deshpande A, Sidiropoulos DN, Lopez-Vidal T, Heiland R, Kagohara LT, Anders RA, Zheng L, Jaffee EM, Stein-O'Brien G, Macklin P, Fertig EJ.   +15 more
europepmc   +1 more source

Morpheus: a fragment-based algorithm to predict fold-switching behaviour in proteins across proteomes. [PDF]

Bioinformatics
Subramanian V, Appadurai R, Venkatesh H, Sekhar A, Srivastava A.   +4 more
europepmc   +1 more source

Introduction to Machine Learning and Bioinformatics [PDF]

Markus Schmidberger
core   +1 more source

Identifying SUMOylation-related genes in liver fibrosis with bioinformatics and experimental models for diagnostic insights

Zhiwei Su, Yuxue Ding, Juan Xue, Jun Sun, Chunyan Ji   +4 more
openalex   +1 more source