Results 271 to 280 of about 1,477,984 (353)

#71 Dysregulation of ITGAM and ITGB2 in the pathogenesis of diabetic kidney disease—results from bioinformatics analysis and in vitro studies [PDF]

Desmond Y. H. Yap, Ruiyan Xie, Sher Ka Ho Jason, Sin Yu Cindy Tang, Qiongli Wu   +4 more
openalex   +1 more source

AntigenApp: a laboratory data management system for nanobody generation and sequence analysis. [PDF]

Bioinformatics
Lubbock ALR, Eyssen LE, Parker K, Basham M, Shemilt LA, Owens RJ.   +5 more
europepmc   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Multi-Cloud Performance and Security-driven Brokering for Bioinformatics Workflows (White Paper)

, 2020
Saptarshi Debroy, Prasad Calyam, Trupti Joshi   +2 more
openalex   +1 more source

Big Data Bioinformatics

, 2016
Xue-wen Chen, Jean Gao
openalex   +2 more sources

13CFLUX - third-generation high-performance engine for isotopically (non)stationary 13C metabolic flux analysis. [PDF]

Bioinformatics
Stratmann A, Beyß M, Jadebeck JF, Wiechert W, Nöh K.   +4 more
europepmc   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Structural, functional, and phylogenetic studies of cytochrome P450 (CYP) enzyme in seed plants by bioinformatics tools

, 2017
Maryam Darabi, Samin Seddigh, Mina Abarshahr   +2 more
openalex   +1 more source

ImmunoPepper: extracting personalized peptides from complex splicing graphs. [PDF]

Bioinformatics
Prélot L, Chen J, Hüser M, Kahles A, Rätsch G.   +4 more
europepmc   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source